Electrospun nanofibers for improved angiogenesis: promises for tissue engineering applications

S Nazarnezhad, F Baino, HW Kim, TJ Webster… - Nanomaterials, 2020 - mdpi.com
Angiogenesis (or the development of new blood vessels) is a key event in tissue
engineering and regenerative medicine; thus, a number of biomaterials have been …

Regulation of macrophage polarization through surface topography design to facilitate implant-to-bone osteointegration

Y Zhu, H Liang, X Liu, J Wu, C Yang, TM Wong… - Science …, 2021 - science.org
Proper immune responses are critical for successful biomaterial implantation. Here, four
scales of honeycomb-like TiO2 structures were custom made on titanium (Ti) substrates to …

Titanium dioxide nanotubes as drug carriers for infection control and osteogenesis of bone implants

K Wang, H Jin, Q Song, J Huo, J Zhang, P Li - Drug Delivery and …, 2021 - Springer
Titanium implants have been widely used as one of the most effective treatments of bone
defects. However, the lack of osteogenesis and bacteria-resistant activities result in high …

Zinc‐modified sulfonated polyetheretherketone surface with immunomodulatory function for guiding cell fate and bone regeneration

W Liu, J Li, M Cheng, Q Wang, KWK Yeung… - Advanced …, 2018 - Wiley Online Library
The cytokines released by immune cells are considered important factors to induce bone
tissue regeneration. However, the pathway of those bone‐targeting macrophage cytokines …

Promoting in vivo early angiogenesis with sub-micrometer strontium-contained bioactive microspheres through modulating macrophage phenotypes

F Zhao, B Lei, X Li, Y Mo, R Wang, D Chen, X Chen - Biomaterials, 2018 - Elsevier
Early vascularization capacity of biomaterials plays an essential role in efficient wound
healing and tissue regeneration, especially in large tissue tension implanting position such …

Tuning the surface potential to reprogram immune microenvironment for bone regeneration

M Li, X Chu, D Wang, L Jian, L Liu, M Yao, D Zhang… - Biomaterials, 2022 - Elsevier
The induction of a suitable immune microenvironment by implant is essential for fast bone
regeneration. Surface potential is a critical factor that influences immune cells behavior. We …

Valence state manipulation of cerium oxide nanoparticles on a titanium surface for modulating cell fate and bone formation

J Li, J Wen, B Li, W Li, W Qiao, J Shen, W Jin… - Advanced …, 2018 - Wiley Online Library
Understanding cell–biomaterial interactions is critical for the control of cell fate for tissue
engineering and regenerative medicine. Here, cerium oxide nanoparticles (CeONPs) are …

Mussel-inspired polydopamine coating: a general strategy to enhance osteogenic differentiation and osseointegration for diverse implants

H Wang, C Lin, X Zhang, K Lin, X Wang… - ACS applied materials …, 2019 - ACS Publications
Surface modifications play an important role in endowing implant surface with excellent
biocompatibility and bioactivity. Among the bioinspired surface modifications, the mussel …

Novel nanoparticles of cerium-doped zeolitic imidazolate frameworks with dual benefits of antibacterial and anti-inflammatory functions against periodontitis

X Li, M Qi, C Li, B Dong, J Wang, MD Weir… - Journal of Materials …, 2019 - pubs.rsc.org
Periodontitis is a common bacteria-borne inflammatory disease that can damage the
supporting structures of teeth, eventually leading to tooth loss and systemic inflammations …

Sustained release of dexamethasone from 3D-printed scaffolds modulates macrophage activation and enhances osteogenic differentiation

M Majrashi, A Kotowska, D Scurr… - … Applied Materials & …, 2023 - ACS Publications
Enhancing osteogenesis via modulating immune cells is emerging as a new approach to
address the current challenges in repairing bone defects and fractures. However, much …