Evaluation of modified gum karaya as carrier for the dissolution enhancement of poorly water-soluble drug nimodipine

GVMM Babu, CDS Prasad, KVR Murthy - International journal of …, 2002 - Elsevier
Modified gum karaya (MGK), a recently developed excipient was evaluated as carrier for
dissolution enhancement of poorly soluble drug, nimodipine (NM). The advantages of MGK …

Development and evaluation of glyburide fast dissolving tablets using solid dispersion technique

M Valleri, P Mura, F Maestrelli, M Cirri… - Drug development and …, 2004 - Taylor & Francis
Glyburide is a poorly water‐soluble oral hypoglycemic agent, with problems of variable
bioavailability and bio‐inequivalence related to its poor water‐solubility. This work …

Study of the physicochemical properties and stability of solid dispersions of loperamide and PEG6000 prepared by spray drying

I Weuts, D Kempen, G Verreck, A Decorte… - European journal of …, 2005 - Elsevier
Solid dispersions of PEG6000 and loperamide—a poorly water-soluble agent—were
prepared by spray drying. Their physicochemical properties were evaluated immediately …

Evaluation of controlled-release polar lipid microparticles

M Savolainen, C Khoo, H Glad, C Dahlqvist… - International journal of …, 2002 - Elsevier
The aim of the present study was to prepare controlled-release tablets of poorly-soluble
drug, felodipine, and various erodable lipophilic excipients. Spray chilling was used to …

Evaluation of polar lipid–hydrophilic polymer microparticles

M Savolainen, J Herder, C Khoo, K Lövqvist… - International journal of …, 2003 - Elsevier
The aim of the present study was to prepare controlled-release tablets of poorly-soluble
drug, felodipine. Spray chilling was used to formulate the drug, the polar lipids and the …

Influence of the microwave technology on the physical–chemical properties of solid dispersion with Nimesulide

M Moneghini, G Zingone, N De Zordi - Powder technology, 2009 - Elsevier
This work describes a new approach to prepare solvent-free solid dispersions (SDs) for
Nimesulide (NMS), involving the use of microwaves irradiation (MW). In particular, the …

Physicochemical characterization of spray dried ternary micro-complexes of cefuroxime axetil with hydroxypropyl-β-cyclodextrin

M Shah, Y Pore, S Dhawale, K Burade… - Journal of Inclusion …, 2013 - Springer
The physicochemical properties of spray dried micro-complexes of cefuroxime axetil (CFA)
with hydroxypropyl-β-cyclodextrin (HPβCD) in presence and/or absence of ternary …

Solubilization of naproxen: experimental data and computational tools

E Mohammadian, A Jouyban, M Barzegar-Jalali… - Journal of Molecular …, 2019 - Elsevier
A number of trained models based on the Jouyban-Acree model were proposed for
prediction of naproxen (NAP) solubility in the cosolvency systems. The predictive cosolvency …

Ternary naproxen: β-cyclodextrin: polyethylene glycol complex formation

M Valero, C Carrillo, LJ Rodrı́guez - International journal of pharmaceutics, 2003 - Elsevier
The aim of this study was to investigate the effect of the presence of the water-soluble
polymer polyethylene glycol (PEG)—MW= 35000g/mol—on the complexation of the …

Response surface methodology to obtain naproxen controlled release tablets from its microspheres with Eudragit L100-55

AA Zaghloul, SR Vaithiyalingam, J Faltinek… - Journal of …, 2001 - Taylor & Francis
Purpose: Naproxen CR tablets have been obtained from its microspheres prepared by
coprecipitation with Eudragit L100-55. The purpose of this work was to evaluate the main …