Cell-Mediated Immunological Biomarkers and Their Diagnostic Application in Livestock and Wildlife Infected With Mycobacterium bovis

K Smith, L Kleynhans, RM Warren, WJ Goosen… - Frontiers in …, 2021 - frontiersin.org
Mycobacterium bovis has the largest host range of the Mycobacterium tuberculosis complex
and infects domestic animal species, wildlife, and humans. The presence of global wildlife …

[HTML][HTML] Review Canine Tuberculosis–An Emerging Concern

EN Barker, C O'Halloran, DA Gunn-Moore - The Veterinary Journal, 2024 - Elsevier
Canine mycobacterial disease was first recognised over 100 years ago but is now an
emerging concern. All reported cases of tuberculous disease in dogs have been caused by …

Advancing animal tuberculosis surveillance using culture-independent long-read whole-genome sequencing

G Ghielmetti, J Loubser, TJ Kerr, T Stuber… - Frontiers in …, 2023 - frontiersin.org
Animal tuberculosis is a significant infectious disease affecting both livestock and wildlife
populations worldwide. Effective disease surveillance and characterization of …

Biomarkers of cell-mediated immunity to bovine tuberculosis

MV Palmer, TC Thacker, MM Rabideau… - Veterinary immunology …, 2020 - Elsevier
Whole blood based assays, particularly interferon gamma (IFN-γ) release assays (IGRAs),
are used for the diagnosis of both bovine and human tuberculosis (TB). The aim of the …

Detection of Mycobacterium tuberculosis complex DNA in oronasal swabs from infected African buffaloes (Syncerus caffer)

C Clarke, DV Cooper, MA Miller, WJ Goosen - Scientific Reports, 2022 - nature.com
Abstract Mycobacterium bovis (M. bovis), a member of the Mycobacterium tuberculosis
complex (MTBC), is the causative agent of bovine TB (bTB) in animals. Spread occurs …

Novel molecular transport medium used in combination with Xpert MTB/RIF ultra provides rapid detection of Mycobacterium bovis in African buffaloes

C Clarke, K Smith, SJ Goldswain, C Helm… - Scientific Reports, 2021 - nature.com
Mycobacterium bovis is the causative agent of bovine tuberculosis (bTB) in wildlife.
Confirmation of M. bovis infection relies on mycobacterial culture, which is time-consuming …

Insights into mycobacteriome composition in Mycobacterium bovis-infected African buffalo (Syncerus caffer) tissue samples

G Ghielmetti, TJ Kerr, N Bernitz, SK Mhlophe… - Scientific Reports, 2024 - nature.com
Animal tuberculosis significantly challenges global health, agriculture, and wildlife
conservation efforts. Mycobacterial cultures are resource-intensive, time-consuming, and …

Genome-Wide Association Study Reveals Quantitative Trait Loci and Candidate Genes Associated with High Interferon-gamma Production in Holstein Cattle Naturally …

G Badia-Bringué, M Canive, P Vázquez… - International Journal of …, 2024 - mdpi.com
Mycobacterium bovis (Mb) is the causative agent of bovine tuberculosis (bTb). Genetic
selection aiming to identify less susceptible animals has been proposed as a …

Test Characteristics of Assays to Detect Mycobacterium bovis Infection in High-Prevalence African Buffalo (Syncerus caffer) Herds

N Bernitz, TJ Kerr, C de Waal… - The Journal of …, 2020 - meridian.allenpress.com
A herd of African buffaloes (Syncerus caffer) was tested for Mycobacterium bovis infection
using three cytokine release assays. All animals were subsequently euthanized and …

Effect of a recent parenteral dexamethasone and ketoprofen administration on the immunological diagnosis of tuberculosis in goats

J Ortega, L De Juan, IA Sevilla, JM Garrido… - Frontiers in Veterinary …, 2022 - frontiersin.org
Caprine tuberculosis (TB) is a zoonosis caused by members of the Mycobacterium
tuberculosis complex (MTBC). Caprine TB eradication programmes are based mainly on …