Clinical translation of long-acting drug delivery formulations

W Li, J Tang, D Lee, TR Tice… - Nature Reviews …, 2022 - nature.com
Most pharmaceuticals are given using short-acting formulations that require frequent
administration, which can negatively affect patient compliance and increase failure risks …

Bone biomaterials and interactions with stem cells

C Gao, S Peng, P Feng, C Shuai - Bone research, 2017 - nature.com
Bone biomaterials play a vital role in bone repair by providing the necessary substrate for
cell adhesion, proliferation, and differentiation and by modulating cell activity and function. In …

[HTML][HTML] Solid implantable devices for sustained drug delivery

E Magill, S Demartis, E Gavini, AD Permana… - Advanced Drug Delivery …, 2023 - Elsevier
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug
administration routes. Oral and injectable drug administration are the most common routes …

The next frontier in melt electrospinning: taming the jet

TM Robinson, DW Hutmacher… - Advanced Functional …, 2019 - Wiley Online Library
There is a specialized niche for the electrohydrodynamic jetting of melts, from biomedical
products to filtration and soft matter applications. The next frontier includes optics …

[HTML][HTML] Long-acting microneedle formulations

LK Vora, AH Sabri, Y Naser, A Himawan… - Advanced Drug Delivery …, 2023 - Elsevier
The minimally-invasive and painless nature of microneedle (MN) application has enabled
the technology to obviate many issues with injectable drug delivery. MNs not only administer …

Nanoparticles used in dentistry: A review

S Priyadarsini, S Mukherjee, M Mishra - Journal of oral biology and …, 2018 - Elsevier
Nanotechnology is widely used in our day to day life including its use in medicine. Using
nanotechnology, it is easy to analyze and manipulate atoms, chemical bonds and molecules …

Injectable bottlebrush hydrogels with tissue-mimetic mechanical properties

F Vashahi, MR Martinez, E Dashtimoghadam… - Science …, 2022 - science.org
Injectable hydrogels are desired in many biomedical applications due to their minimally
invasive deployment to the body and their ability to introduce drugs. However, current …

[HTML][HTML] 3D-printed polycaprolactone-chitosan based drug delivery implants for personalized administration

Y Yang, H Wu, Q Fu, X Xie, Y Song, M Xu, J Li - Materials & Design, 2022 - Elsevier
Fused deposition molding (FDM) can complete most complex preparation of drug delivery
implants to meet the personalized needs of patients. However, the drug activity has strict …

Drug-loaded biomaterials for orthopedic applications: A review

D Aggarwal, V Kumar, S Sharma - Journal of Controlled Release, 2022 - Elsevier
Drug-eluting implants are one of the leading implant technologies to facilitate the healing
capacity of bones by eliminating implant-associated infections. Treatment of the infections …

Biopolymers for antitumor implantable drug delivery systems: recent advances and future outlook

S Talebian, J Foroughi, SJ Wade, KL Vine… - Advanced …, 2018 - Wiley Online Library
In spite of remarkable improvements in cancer treatments and survivorship, cancer still
remains as one of the major causes of death worldwide. Although current standards of care …