Bladder cancer immune-related markers: diagnosis, surveillance, and prognosis

T Yang, W Luo, J Yu, H Zhang, M Hu… - Frontiers in Immunology, 2024 - frontiersin.org
As an immune-related tumor type, bladder cancer has been attracting much attention in the
study of its markers. In recent years, researchers have made rapid progress in the study of …

Urine‐based liquid biopsy in bladder cancer: opportunities and challenges

G Wang, W Jin, Z Xu, L Ju, D Shan, S Li… - Clinical and …, 2023 - Wiley Online Library
Bladder cancer (BLCA) is a most common urological tumours with high rate of recurrence,
which needs long‐term of follow‐up. To date, diagnosis and surveillance of BLCA still rely …

Urine scRNAseq reveals new insights into the bladder tumor immune microenvironment

MA Tran, D Youssef, S Shroff, D Chowhan… - Journal of Experimental …, 2024 - rupress.org
Due to bladder tumors' contact with urine, urine-derived cells (UDCs) may serve as a
surrogate for monitoring the tumor microenvironment (TME) in bladder cancer (BC) …

Intratumoral PD1+CD38+Tim3+ CD8+ T Cells in Pre-BCG Tumor Tissues Are Associated with Poor Responsiveness to BCG Immunotherapy in Patients with Non …

D Basak, S Mondal, SK Srivastava, D Sarkar, I Sarkar… - Cells, 2023 - mdpi.com
Intravesical immunotherapy with Bacillus Calmette–Guerin (BCG) is a standard of care
therapy for non-muscle invasive bladder cancer (NMIBC), which accounts for about 75% of …

BCG priming followed by a novel interleukin combination activates Natural Killer cells to selectively proliferate and become anti-tumour long-lived effectors

MJ Felgueres, G Esteso, ÁF García-Jiménez… - Scientific Reports, 2024 - nature.com
The short-lived nature and heterogeneity of Natural Killer (NK) cells limit the development of
NK cell-based therapies, despite their proven safety and efficacy against cancer. Here, we …

Intracellular Major Histocompatibility Complex Class II and CXC Motif Chemokine Ligand 10-Expressing Neutrophils Indicate the State of Anti-Tumor Activity Induced …

Y Takeda, T Kato, S Sabrina, S Naito, H Ito, N Emi… - Biomedicines, 2023 - mdpi.com
(1) Background: Inflammatory responses induce the formation of both anti-tumor and pro-
tumor neutrophils known as myeloid-derived suppressor cells (MDSCs). Intermittent …

A comprehensive analysis of immune response in patients with non-muscle-invasive bladder cancer

G Celada Luis, E Albers Acosta, H de la Fuente… - Cancers, 2023 - mdpi.com
Simple Summary A comprehensive characterization of cell subpopulations involved in the
immune response against bladder cancer has not been performed so far. In addition, due to …

Advancements in Urothelial Cancer Care: Optimizing Treatment for Your Patient

G Hemenway, JF Anker, P Riviere, BS Rose… - American Society of …, 2024 - ascopubs.org
The standard treatment paradigm for muscle invasive bladder cancer has been neoadjuvant
cisplatin-based chemotherapy followed by radical cystectomy. However, efforts are ongoing …

[PDF][PDF] Intratumoral PD1+CD38+Tim3+ CD8+ T Cells in Pre-BCG Tumor Tissues Are Associated with Poor Responsiveness to BCG Immunotherapy in Patients with …

D Basak, S Mondal, SK Srivastava, D Sarkar, I Sarkar… - 2023 - academia.edu
Intravesical immunotherapy with Bacillus Calmette–Guerin (BCG) is a standard of care
therapy for non-muscle invasive bladder cancer (NMIBC), which accounts for about 75% of …

GENOME-SCALE METHYLATION ANALYSIS IN BLOOD AND TUMOR IDENTIFIES IMMUNE PROFILE, AGE ACCELERATION, AND DNA METHYLATION …

JQ Chen - 2023 - digitalcommons.dartmouth.edu
Bladder cancer patients receive frequent screening due to the high tumor recurrence rate
(more than 60%). Nowadays, the conventional monitoring method relies on cystoscopy …