Unraveling Dilemmas and Lacunae in the Escalating Drug Resistance of Mycobacterium tuberculosis to Bedaquiline, Delamanid, and Pretomanid
Delamanid, bedaquiline, and pretomanid have been recently added in the anti-tuberculosis
(anti-TB) treatment regimens and have emerged as potential solutions for combating drug …
(anti-TB) treatment regimens and have emerged as potential solutions for combating drug …
[HTML][HTML] Epidemiology of extensively drug-resistant tuberculosis among patients with multidrug-resistant tuberculosis: a systematic review and meta-analysis
G Diriba, A Alemu, B Yenew, HH Tola… - International Journal of …, 2023 - Elsevier
Objectives To estimate the pooled proportion of extensively drug-resistant tuberculosis (XDR-
TB) and pre-extensively drug-resistant tuberculosis (pre-XDR-TB) in patients with multidrug …
TB) and pre-extensively drug-resistant tuberculosis (pre-XDR-TB) in patients with multidrug …
Whole Genome Sequencing of Drug Resistant and Drug Susceptible Mycobacterium tuberculosis Isolates From Tigray Region, Ethiopia
LN Welekidan, SA Yimer, E Skjerve… - Frontiers in …, 2021 - frontiersin.org
Background: Tuberculosis, mainly caused by Mycobacterium tuberculosis (Mtb), is an
ancient human disease that gravely affects millions of people annually. We wanted to …
ancient human disease that gravely affects millions of people annually. We wanted to …
Profile and frequency of mutations conferring drug-resistant tuberculosis in the central, Southeastern and Eastern Ethiopia
Purpose Advances in molecular tools that assess genes harboring drug resistance
mutations have greatly improved the detection and treatment of drug-resistant tuberculosis …
mutations have greatly improved the detection and treatment of drug-resistant tuberculosis …
Frequency of rpoB, katG, and inhA Gene Polymorphisms Associated with Multidrug‐Resistant Mycobacterium tuberculosis Complex Isolates among Ethiopian TB …
Tuberculosis (TB) is one of the top 10 causes of mortality and the first killer among infectious
diseases of poverty (IDoPs) worldwide. It disproportionately affects on‐third of the world's …
diseases of poverty (IDoPs) worldwide. It disproportionately affects on‐third of the world's …
Molecular characterization of genetic mutations with fitness loss in pulmonary tuberculosis patients associated with HIV co-infection in Northwest Amhara, Ethiopia
A Seid, M Kassa, Y Girma, E Dereb… - SAGE Open …, 2023 - journals.sagepub.com
Objectives: Molecular approaches to identifying resistance-conferring mutations suggest a
revolution in the field of tuberculosis. The aim of the study was to determine the association …
revolution in the field of tuberculosis. The aim of the study was to determine the association …
Transmission, distribution and drug resistance-conferring mutations of extensively drug-resistant tuberculosis in the Western Cape Province, South Africa
S Oostvogels, SD Ley, TH Heupink… - Microbial …, 2022 - microbiologyresearch.org
Extensively drug-resistant tuberculosis (XDR-TB), defined as resistance to at least isoniazid
(INH), rifampicin (RIF), a fluoroquinolone (FQ) and a second-line injectable drug (SLID), is …
(INH), rifampicin (RIF), a fluoroquinolone (FQ) and a second-line injectable drug (SLID), is …
Patterns and profiles of drug resistance-conferring mutations in Mycobacterium tuberculosis genotypes isolated from tuberculosis-suspected attendees of spiritual …
Purpose This study examined the patterns and frequency of genetic changes responsible for
resistance to first-line (rifampicin and isoniazid), fluoroquinolones, and second-line …
resistance to first-line (rifampicin and isoniazid), fluoroquinolones, and second-line …
Utility of line probe assay in detecting drug resistance and the associated mutations in patients with extrapulmonary tuberculosis in Addis Ababa, Ethiopia
G Diriba, A Kebede, HH Tola, A Alemu… - SAGE Open …, 2022 - journals.sagepub.com
Introduction: Molecular tests allow rapid detection of Mycobacterium tuberculosis and drug
resistance in a few days. Identifying the mutations in genes associated with drug resistance …
resistance in a few days. Identifying the mutations in genes associated with drug resistance …
Targeted next-generation sequencing of Mycobacterium tuberculosis from patient samples: lessons learned from high drug-resistant burden clinical settings in …
MK Mafij Uddin, AM Cabibbe, R Nasrin… - Emerging Microbes & …, 2024 - Taylor & Francis
Lack of appropriate early diagnostic tools for drug-resistant tuberculosis (DR-TB) and their
incomplete drug susceptibility testing (DST) profiling is concerning for TB disease control …
incomplete drug susceptibility testing (DST) profiling is concerning for TB disease control …