Nicotinamide N-methyltransferase (NNMT) is an intracellular methyltransferase, catalyzing
the N-methylation of nicotinamide (NAM) to form 1-methylnicotinamide (1-MNAM), in which …

Nicotinamide N-methyltransferase (NNMT) methylates nicotinamide (NA) to generate 1-
methyl nicotinamide. Since its discovery 70 years ago, the appreciation of the role of NNMT …

Nicotinamide N-methyltransferase (NNMT) methylates nicotinamide (vitamin B3) to generate
1-methylnicotinamide (MNA). NNMT overexpression has been linked to a variety of …

Nicotinamide N-methyltransferase (NNMT) catalyzes the methylation of nicotinamide to form
N-methylnicotinamide. Overexpression of NNMT is associated with a variety of diseases …

Nicotinamide N-methyltransferase (NNMT) is a cytosolic enzyme that catalyzes the transfer
of a methyl group from the co-factor S-adenosyl-L-methionine (SAM) onto the substrate …

Melanoma accounts for less than 5% of all cutaneous neoplasms but is responsible for the
greater part of skin cancer–related deaths. Therefore, the identification of molecules that …

A recently discovered bisubstrate inhibitor of Nicotinamide N-methyltransferase (NNMT) was
found to be highly potent in biochemical assays with a single digit nanomolar IC50 value but …

Nicotinamide N-methyltransferase (NNMT) methylates nicotinamide to form 1-
methylnicotinamide (MNA) using S-adenosyl-L-methionine (SAM) as the methyl donor. The …

Gastrointestinal (GI) neoplasms include esophageal, gastric, colorectal, hepatic, and
pancreatic cancers. They are characterized by asymptomatic behavior, being responsible for …

Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation reaction of
nicotinamide, using S-adenosyl-L-methionine as the methyl donor. Enzyme overexpression …