Respiratory syncytial virus

A Jha, H Jarvis, C Fraser… - SARS, MERS and other …, 2016 - library.oapen.org
Respiratory syncytial virus (RSV) infection has an estimated global incidence of 33 million
cases in children younger than 5 years, with 10% requiring hospital admission and up to …

[HTML][HTML] Immunity to RSV in early-life

L Lambert, AM Sagfors, PJM Openshaw… - Frontiers in …, 2014 - frontiersin.org
Respiratory Syncytial Virus (RSV) is the commonest cause of severe respiratory infection in
infants, leading to over 3 million hospitalizations and around 66,000 deaths worldwide each …

[HTML][HTML] RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

A Jozwik, MS Habibi, A Paras, J Zhu, A Guvenel… - Nature …, 2015 - nature.com
In animal models, resident memory CD8+ T (Trm) cells assist in respiratory virus elimination
but their importance in man has not been determined. Here, using experimental human …

Aetiology of childhood pneumonia in a well vaccinated South African birth cohort: a nested case-control study of the Drakenstein Child Health Study

HJ Zar, W Barnett, A Stadler… - The Lancet …, 2016 - thelancet.com
Background Pneumonia is a leading cause of mortality and morbidity in children globally.
The cause of pneumonia after introduction of the 13-valent pneumococcal conjugate …

[HTML][HTML] WHO consultation on respiratory syncytial virus vaccine development report from a World Health Organization meeting held on 23–24 March 2015

K Modjarrad, B Giersing, DC Kaslow, PG Smith… - Vaccine, 2016 - Elsevier
Respiratory syncytial virus (RSV) is a globally prevalent cause of lower respiratory infection
in neonates and infants. Despite its disease burden, a safe and effective RSV vaccine has …

[HTML][HTML] CX3CR1 is expressed in differentiated human ciliated airway cells and co-localizes with respiratory syncytial virus on cilia in a G protein-dependent manner

KI Jeong, PA Piepenhagen, M Kishko, JM DiNapoli… - PloS one, 2015 - journals.plos.org
Respiratory syncytial virus (RSV) is the principal cause of bronchiolitis in infants and a
significant healthcare problem. The RSV Glycoprotein (G) mediates attachment of the virus …

Group B streptococcus and respiratory syncytial virus immunisation during pregnancy: a landscape analysis

PT Heath, FJ Culley, CE Jones… - The Lancet Infectious …, 2017 - thelancet.com
Group B streptococcus and respiratory syncytial virus are leading causes of infant morbidity
and mortality worldwide. No licensed vaccines are available for either disease, but vaccines …

[HTML][HTML] Epitope-specific airway-resident CD4+ T cell dynamics during experimental human RSV infection

A Guvenel, A Jozwik, S Ascough… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Respiratory syncytial virus (RSV) is an important cause of acute pulmonary
disease and one of the last remaining major infections of childhood for which there is no …

[HTML][HTML] Induction and subversion of human protective immunity: contrasting influenza and respiratory syncytial virus

S Ascough, S Paterson, C Chiu - Frontiers in Immunology, 2018 - frontiersin.org
Respiratory syncytial virus (RSV) and influenza are among the most important causes of
severe respiratory disease worldwide. Despite the clinical need, barriers to developing …

Dimerization of matrix protein is required for budding of respiratory syncytial virus

A Förster, GN Maertens, PJ Farrell, M Bajorek - Journal of virology, 2015 - Am Soc Microbiol
Respiratory syncytial virus (RSV) infects epithelial cells of the respiratory tract and is a major
cause of bronchiolitis and pneumonia in children and the elderly. The virus assembles and …