The long and short non-coding RNAs modulating EZH2 signaling in cancer

S Mirzaei, MH Gholami, K Hushmandi… - Journal of hematology & …, 2022 - Springer
Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in
encoding proteins. However, they participate in developmental and biological processes …

Are nano-pesticides really meant for cleaner production? An overview on recent developments, benefits, environmental hazards and future prospectives

N Rani, A Duhan, A Pal, P Kumari, RK Beniwal… - Journal of Cleaner …, 2023 - Elsevier
The world is seeking hard for sustainable agricultural practices with one of the prime
objectives to improve crop yield through effective pest management. Scientific diaspora has …

Surfactant-free, self-assembled nanomicelles-based transdermal hydrogel for safe and targeted delivery of methotrexate against rheumatoid arthritis

M Qindeel, D Khan, N Ahmed, S Khan… - ACS …, 2020 - ACS Publications
Methotrexate (MTX) is the first line agent for therapy against rheumatoid arthritis (RA);
however, orally its efficacy is hampered by poor solubility, less permeability, short plasma …

Poly ethylene glycol (PEG)-Related controllable and sustainable antidiabetic drug delivery systems

Y Fu, Y Ding, L Zhang, Y Zhang, J Liu, P Yu - European journal of medicinal …, 2021 - Elsevier
Diabetes mellitus is one of the most challenging threats to global public health. To improve
the therapy efficacy of antidiabetic drugs, numerous drug delivery systems have been …

[HTML][HTML] A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells

S Magkouta, D Veroutis, A Pousias… - Molecular Cell, 2023 - cell.com
Cellular senescence is a stress-response mechanism implicated in various physiological
processes, diseases, and aging. Current detection approaches have partially addressed the …

Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐infrared light mediated cancer therapy

R Prasad, NK Jain, AS Yadav, DS Chauhan… - Communications …, 2020 - nature.com
Developing a nanotheranostic agent with better image resolution and high accumulation
into solid tumor microenvironment is a challenging task. Herein, we established a light …

Ganetespib with methotrexate acts synergistically to impede NF-κB/p65 signaling in human lung cancer A549 cells

G Subaiea, SMD Rizvi, HKS Yadav, T Al Hagbani… - Pharmaceuticals, 2023 - mdpi.com
Among the various types of cancer, lung cancer accounts for the highest number of fatalities
across the globe. A combination of different cancer chemotherapeutics is regarded as an …

Preparation of colloidal nanoparticles PVA-PHEMA from hydrolysis of copolymers of PVAc-PHEMA as anticancer drug carriers

M Shahrousvand, M Hajikhani, L Nazari… - …, 2022 - iopscience.iop.org
The novel pH-responsive polymer nanoparticles have been widely used for drug delivery
and cancer therapy. The pH-sensitive nanoparticles include chemical structures that can …

Improvement of pharmacologically relevant properties of methotrexate by solid dispersion with Pluronic F127

M Agafonov, S Ivanov, I Terekhova - Materials Science and Engineering: C, 2021 - Elsevier
Solid dispersion with Pluronic F127 was proposed as alternative approach to modify the
pharmacologically relevant properties of methotrexate (MTX). Solid dispersion of MTX with …

pH-responsive star-shaped poly (ε-carprolactone)-co-poly maleic anhydride micelles for synergistic breast cancer combination chemotherapy

A Rahmani, S Salmanipour, Y Nami… - Reactive and Functional …, 2023 - Elsevier
Polymeric micelles produced from amphiphilic copolymers, are considered promising drug
delivery platforms. Because of their ability to co-deliver hydrophilic (Dox) and hydrophobic …