Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank

W Xu, I Mesa-Eguiagaray, DM Morris, C Wang… - Nature …, 2025 - nature.com
Bone marrow adipose tissue is a distinct adipose subtype comprising more than 10% of fat
mass in healthy humans. However, the functions and pathophysiological correlates of this …

Genome-wide cross-disease analyses highlight causality and shared biological pathways of type 2 diabetes with gastrointestinal disorders

EO Adewuyi, T Porter, EK O'Brien, O Olaniru… - Communications …, 2024 - nature.com
Studies suggest links between diabetes and gastrointestinal (GI) traits; however, their
underlying biological mechanisms remain unclear. Here, we comprehensively assess the …

Sex hormone imbalance and rheumatoid arthritis in American men: a cross-sectional analysis from NHANES 2011–2016

P Wen, Y Wang, M Yang, X Qiao, P Yang, S Hu… - Frontiers in …, 2024 - frontiersin.org
Background Emerging evidence suggests that sex hormones, particularly testosterone and
sex hormone-binding globulin (SHBG), play a critical role in the pathophysiology of …

Serum biochemical markers and rheumatoid arthritis: Insights from observational study and Mendelian randomization analysis

F Fan, H Tan, Y Xie, H Qin, C Zhang, H Wang, W Yan… - 2024 - researchsquare.com
Objectives: To identify the specific serum biochemical markers that exhibit causal
associations with the risk rheumatoid arthritis (RA) Methods: A cross-sectional study based …