The notion that stress and cancer are interlinked has dominated lay discourse for decades.
More recent animal studies indicate that stress can substantially facilitate cancer …

The blood-brain barrier (BBB), constituted by an extensive network of endothelial cells (ECs)
together with neurons and glial cells, including microglia, forms the neurovascular unit …

We present a publicly available dataset of 227 healthy participants comprising a young (N=
153, 25.1±3.1 years, range 20–35 years, 45 female) and an elderly group (N= 74, 67.6±4.7 …

The gut–brain axis refers to the bidirectional communication between the gut and the brain.
Four information carriers (vagal and spinal afferent neurons, immune mediators such as …

Cytokines are molecules secreted by peripheral immune cells, microglia, astrocytes and
neurons in the central nervous system. Peripheral or central inflammation is characterized …

Purpose Numerous studies have examined the comorbidity of depression with cancer, and
some have indicated that depression may be associated with cancer progression or survival …

Fatigue is one of the most common and distressing side effects of cancer and its treatment,
and may persist for years after treatment completion in otherwise healthy survivors. Guided …

Sustained stress triggers series of changes in the brain and the body. At the early stage of
stress, the activated hypothalamus‐pituitary‐adrenal (HPA) axis and sympathetic nervous …

Epidemiologic evidence increasingly has supported the role of biobehavioral risk factors
such as social adversity, depression, and stress in cancer progression. This review …

Considering the complexity of the current framework in oncology, the relevance of animal
models in biomedical research is critical in light of the capacity to produce valuable data with …