Basic research and clinical chemoprevention trials support the protective role of selenium in
cancer prevention but the mechanisms based on the molecular level remain to be fully …

The laboratory mouse has long been an important tool in the study of the biology and
genetics of human cancer. With the advent of genetic engineering techniques, DNA …

A distinction is made between viability, metabolic toxicity, and cell survival assays and the
implications of each for the design of assays. Protocols are provided for measuring viability …

Staphylococcus aureus causes a spectrum of human infection. Diagnostic delays and
uncertainty lead to treatment delays and inappropriate antibiotic use. A growing literature …

Breast cancer is commonest cancer in women worldwide. Elucidation of underlying biology
and molecular pathways is necessary for improving therapeutic options and clinical …

An important new concept associated with estrogen receptor (ER) function in breast cancer
is that ER status/phenotype is multifaceted. In particular, the two full‐length, ligand binding …

Biomarkers, including cytokines, can help in the diagnosis, prognosis, and prediction of
treatment response across a wide range of disease settings. Consequently, the recent …

Objective Previous studies have identified differences in gene mutations among endometrial
cancers from whites and blacks suggesting that differences in tumor biology may explain …

Background Breast cancer is a complex multifactorial genetic disease. Among other factors,
race and, to an even greater extent, viruses are known to influence the development of this …

The development of breast cancer is thought to occur through a multi-step process. The
majority of breast cancers likely develop over extended periods of time arising from early …