Nasopharyngeal carcinoma: an evolving paradigm

KCW Wong, EP Hui, KW Lo, WKJ Lam… - Nature reviews Clinical …, 2021 - nature.com
The past three decades have borne witness to many advances in the understanding of the
molecular biology and treatment of nasopharyngeal carcinoma (NPC), an Epstein–Barr virus …

Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond

L Keller, Y Belloum, H Wikman, K Pantel - British journal of cancer, 2021 - nature.com
Cell-free DNA (cfDNA) derived from tumours is present in the plasma of cancer patients. The
majority of currently available studies on the use of this circulating tumour DNA (ctDNA) deal …

[HTML][HTML] Investigation of long COVID prevalence and its relationship to Epstein-Barr virus reactivation

JE Gold, RA Okyay, WE Licht, DJ Hurley - Pathogens, 2021 - mdpi.com
Pathogens | Free Full-Text | Investigation of Long COVID Prevalence and Its Relationship to
Epstein-Barr Virus Reactivation Next Article in Journal Epidemiological Aspects of Maternal …

[HTML][HTML] Anti–Epstein–Barr virus BNLF2b for mass screening for nasopharyngeal cancer

T Li, F Li, X Guo, C Hong, X Yu, B Wu… - … England Journal of …, 2023 - Mass Medical Soc
Background Population screening of asymptomatic persons with Epstein–Barr virus (EBV)
DNA or antibodies has improved the diagnosis of nasopharyngeal carcinoma and survival …

[HTML][HTML] Epstein-Barr virus and systemic autoimmune diseases

G Houen, NH Trier - Frontiers in immunology, 2021 - frontiersin.org
Epstein-Barr Virus (EBV) is an extremely successful human herpes virus, which infects
essentially all human beings at some time during their life span. EBV infection and the …

Circulating tumor DNA and liquid biopsy in oncology

DW Cescon, SV Bratman, SM Chan, LL Siu - Nature cancer, 2020 - nature.com
Techniques for analyzing circulating tumor DNA (ctDNA) to detect, characterize and monitor
cancer have matured rapidly. An increasing body of clinical evidence is demonstrating the …

Toward the early detection of cancer by decoding the epigenetic and environmental fingerprints of cell-free DNA

Y Van Der Pol, F Mouliere - Cancer cell, 2019 - cell.com
Widespread adaptation of liquid biopsy for the early detection of cancer has yet to reach
clinical utility. Circulating tumor DNA is commonly detected though the presence of genetic …

Epigenetic analysis of cell-free DNA by fragmentomic profiling

Q Zhou, G Kang, P Jiang, R Qiao… - Proceedings of the …, 2022 - National Acad Sciences
Cell-free DNA (cfDNA) fragmentation patterns contain important molecular information
linked to tissues of origin. We explored the possibility of using fragmentation patterns to …

The role of Epstein–Barr virus in nasopharyngeal carcinoma

ZY Su, PY Siak, CO Leong, SC Cheah - Frontiers in Microbiology, 2023 - frontiersin.org
Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated
with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC …

Longitudinal on-treatment circulating tumor DNA as a biomarker for real-time dynamic risk monitoring in cancer patients: the EP-SEASON study

J Lv, LX Xu, ZX Li, L Lin, CF Wu, TQ Quan, ZC Zhen… - Cancer cell, 2024 - cell.com
Recurrence risks of cancer patient can change during treatment as a result of treatment-
related tumor evolution. However, biomarkers that can monitor these changes are lacking …