In the past decade, novel lamellar keratoplasty techniques such as Deep Anterior Lamellar
Keratoplasty (DALK) for anterior keratoplasty and Descemet stripping automated endothelial …

Advances in our understanding of the structure and function of the lymphatic system have
made it possible to identify its role in a variety of disease processes. Because it is involved …

The cornea is unique because of its complete avascularity. Corneal neovascularization
(CNV) can result from a variety of etiologies including contact lens wear; corneal infections; …

Human corneal transplantation (keratoplasty) is typically considered to have superior short-
and long-term outcomes and lower requirement for immunosuppression compared to solid …

The cornea is the most commonly transplanted tissue in medicine. The main cause of
corneal graft failure is allograft rejection. The incidence of graft rejection depends on the …

High-risk (HR) corneal transplantation presents a formidable challenge, with over 50% of
grafts experiencing rejection despite intensive postoperative care involving frequent topical …

Corneal transplantation is one of the most prevalent and successful forms of solid tissue
transplantation. Despite favorable outcomes, immune-mediated graft rejection remains the …

Ocular drug delivery has been significantly advanced for not only pharmaceutical
compounds, such as steroids, nonsteroidal anti-inflammatory drugs, immune modulators …

Background Corneal allograft survival dramatically decreases in hosts with inflamed or
vascularized recipient beds. We have previously shown that in rejected corneal allografts …

Topical corticosteroid eye drop is the mainstay for preventing and treating corneal graft
rejection. While the frequent topical corticosteroid use is associated with risk of intraocular …