Organic cation transporters in psychiatric and substance use disorders

LE Honan, R Fraser-Spears, LC Daws - Pharmacology & therapeutics, 2024 - Elsevier
Psychiatric and substance use disorders inflict major public health burdens worldwide. Their
widespread burden is compounded by a dearth of effective treatments, underscoring a dire …

Summarizing studies using constitutive genetic deficiency to investigate behavioural influences of uptake 2 monoamine transporters

BL Weber, JN Beaver, TL Gilman - Basic & clinical …, 2023 - Wiley Online Library
Burgeoning literature demonstrates that monoamine transporters with high transport
capacity but lower substrate affinity (ie, uptake 2) contribute meaningfully to regulation of …

Heterotypic stressors unmask behavioral influences of PMAT deficiency in mice

BL Weber, MM Nicodemus, AK Hite… - International Journal of …, 2023 - mdpi.com
Certain life stressors having enduring physiological and behavioral consequences, in part
by eliciting dramatic signaling shifts in monoamine neurotransmitters. High monoamine …

Are there prevalent sex differences in psychostimulant use disorder? A focus on the potential therapeutic efficacy of atypical dopamine uptake inhibitors

M Hersey, MK Bartole, CS Jones, AH Newman… - Molecules, 2023 - mdpi.com
Psychostimulant use disorders (PSUD) affect a growing number of men and women and
exert sizable public health and economic burdens on our global society. Notably, there are …