Erdheim-Chester disease (ECD) is a rare histiocytosis that was recently recognized as a
neoplastic disorder owing to the discovery of recurrent activating MAPK (RAS-RAF-MEK …

Histiocytoses constitute a heterogeneous group of rare disorders, characterised by
infiltration of almost any organ by myeloid cells with diverse macrophage or dendritic cell …

Langerhans cell histiocytosis (LCH) can affect children and adults with a wide variety of
clinical manifestations, including unifocal, single-system multifocal, single-system pulmonary …

ALK-positive histiocytosis is a rare subtype of histiocytic neoplasm first described in 2008 in
3 infants with multisystemic disease involving the liver and hematopoietic system. This entity …

Rosai-Dorfman disease is a rare subtype of non-Langerhans cell histiocytosis. With the last
major report published in 1990, there is a paucity of contemporary data on this disease. Our …

Histiocytic neoplasms are rare hematologic disorders accounting for less than 1% of cancers
of the soft tissue and lymph nodes. Clinical presentation and prognosis of these disorders …

[1] Go A, Hylek E, Phillips K, et al. Prevalence of diagnosed atrial fibrillation in adults
national implications for rhythm management and stroke prevention: the AnTicoagulation …

Histiocytoses are heterogeneous hematopoietic diseases characterized by the accumulation
of CD68 (+) cells with various admixed inflammatory infiltrates. The identification of the …

Erdheim–Chester disease (ECD) is a rare non-Langerhans cell histiocytosis with a putative
neoplastic and inflammatory nature. The disease is driven by mutations in proto-oncogenes …

Erdheim-Chester disease (ECD) and Rosai-Dorfman disease (RDD) are rare non-
Langerhans cell histiocytoses (non-LCHs), for which therapeutic options are limited. MAPK …