Secondary metabolites from higher fungi

HP Chen, JK Liu - Progress in the chemistry of organic natural products …, 2017 - Springer
Secondary metabolites of higher fungi (mushrooms) are an underexplored resource
compared to plant-derived secondary metabolites. An increasing interest in mushroom …

Natural disesquiterpenoids: an update

LF Ma, YL Chen, WG Shan, ZJ Zhan - Natural Product Reports, 2020 - pubs.rsc.org
Covering: July 2010 to August 2019. Previous review: Nat. Prod. Rep., 2011, 28, 594 The
review covers recent progress on the isolation, identification, bioactivity and biomimetic …

Mining Xanthine Oxidase Inhibitors from an Edible Seaweed Pterocladiella capillacea by Using In Vitro Bioassays, Affinity Ultrafiltration LC-MS/MS, Metabolomics …

Y Wang, L Zhou, M Chen, Y Liu, Y Yang, T Lu, F Ban… - Marine Drugs, 2023 - mdpi.com
The prevalence of gout and the adverse effects of current synthetic anti-gout drugs call for
new natural and effective xanthine oxidase (XOD) inhibitors to target this disease. Based on …

Linear triquinane sesquiterpenoids: Their isolation, structures, biological activities, and chemical synthesis

Y Qiu, WJ Lan, HJ Li, LP Chen - Molecules, 2018 - mdpi.com
Linear triquinane sesquiterpenoids represent an important class of natural products. Most of
these compounds were isolated from fungi, sponges, and soft corals, and many of them …

Stereochemical and biosynthetic rationalisation of the tropolone sesquiterpenoids

L Li, RJ Cox - Journal of Fungi, 2022 - mdpi.com
This review summarises the known structures, biological activities, and biosynthetic
pathways of the tropolone sesquiterpenoid family of fungal secondary metabolites …

Metabolic engineering-based rapid characterization of a sesquiterpene cyclase and the skeletons of fusariumdiene and fusagramineol from Fusarium graminearum

G Bian, A Hou, Y Yuan, B Hu, S Cheng, Z Ye, Y Di… - Organic …, 2018 - ACS Publications
The potential power of sesquiterpene synthase FgJ03939 from Fusarium graminearum was
fully exploited in a farnesyl diphosphate-overexpressing Saccharomyces cerevisiae chassis …

Novel Natural Oximes and Oxime Esters with a Vibralactone Backbone from the Basidiomycete Boreostereum vibrans

HP Chen, ZZ Zhao, ZH Li, ZJ Dong, K Wei… - …, 2016 - Wiley Online Library
A variety of novel natural products with significant bioactivities are produced by the
basidiomycete Boreostereum vibrans. In the present study, we describe 16 novel natural …

Stucturally Diverse Sesquiterpenes Produced by a Chinese Tibet Fungus Stereum hirsutum and Their Cytotoxic and Immunosuppressant Activities

QY Qi, JW Ren, LW Sun, LW He, L Bao, W Yue… - Organic …, 2015 - ACS Publications
Two new heterodimeric sesquiterpenes, sterhirsutins C (1) and D (2), along with eight new
sesquiterpenoid derivatives, sterhirsutins E–-L (3–10), were isolated from the culture of …

Fungi: outstanding source of novel chemical scaffolds

Z Liu, JY Zhao, SF Sun, Y Li, YB Liu - Journal of Asian natural …, 2020 - Taylor & Francis
A large number of remarkable studies on the secondary metabolites of fungi have been
conducted in recent years. This review gives an overview of one hundred and sixty-seven …

In Depth Natural Product Discovery from the Basidiomycetes Stereum Species

M Tian, P Zhao, G Li, K Zhang - Microorganisms, 2020 - mdpi.com
Natural metabolites from microorganisms play significant roles in the discovery of drugs,
both for disease treatments in humans, and applications in agriculture. The Basidiomycetes …