Radiation-induced second malignancies (RISM) is one of the important late side effects of
radiation therapy and has an impact on optimal treatment decision-making. Many factors …

In this paper, we discuss the role of particle therapy—a novel radiation therapy (RT) that has
shown rapid progress and widespread use in recent years—in multidisciplinary treatment …

Purpose Proton therapy can allow for superior avoidance of normal tissues. A widespread
consensus has been reached that proton therapy should be used for patients with curable …

We are in the midst of a technological revolution that is providing new insights into human
biology and cancer. In this era of big data, we are amassing large amounts of information …

While proton radiation therapy offers substantially better dose distribution characteristics
than photon radiation therapy in certain clinical applications, data demonstrating a …

Proton beam therapy is a highly conformal form of radiation therapy, which currently
represents an important therapeutic component in multidisciplinary management in …

Simple Summary Medulloblastoma is the most common pediatric brain tumor, comprising
one-third of all pediatric brain tumors, and originating in the posterior fossa of the brain. The …

Medulloblastoma is a common pediatric brain tumor and one of the main types of solid
cancers in children below the age of 10. Recently, cholesterol-lowering “statin” drugs have …

Radiation-induced secondary malignancies are a significant, yet uncommon cause of
morbidity and mortality among cancer survivors. Secondary malignancy risk is dependent …

BACKGROUND The treatment for childhood intracranial ependymoma includes maximal
surgical resection followed by involved‐field radiotherapy, commonly in the form of intensity …