[HTML][HTML] Regulators of collagen crosslinking in developing and adult tendons

AJ Ellingson, NM Pancheri… - European cells & …, 2022 - ncbi.nlm.nih.gov
Tendons are collagen-rich musculoskeletal tissues that possess the mechanical strength
needed to transfer forces between muscles and bones. The mechanical development and …

Modeling inelastic responses using constrained reactive mixtures

GA Ateshian, CT Hung, JA Weiss… - European Journal of …, 2023 - Elsevier
This study reviews the progression of our research, from modeling growth theories for
cartilage tissue engineering, to the formulation of constrained reactive mixture theories to …

Collagen fibril abnormalities in human and mice abdominal aortic aneurysm

B Jones, JR Tonniges, A Debski, B Albert, DA Yeung… - Acta biomaterialia, 2020 - Elsevier
Vascular diseases like abdominal aortic aneurysms (AAA) are characterized by a drastic
remodeling of the vessel wall, accompanied with changes in the elastin and collagen …

Widespread diversity in the transcriptomes of functionally divergent limb tendons

NP Disser, GC Ghahramani, JB Swanson… - The Journal of …, 2020 - Wiley Online Library
Key points Tendon is a hypocellular, matrix‐rich tissue that has been excluded from
comparative transcriptional atlases. These atlases have provided important knowledge …

Elastin is responsible for the rigidity of the ligament under shear and rotational stress: a mathematical simulation study

Y Naya, H Takanari - Journal of Orthopaedic Surgery and Research, 2023 - Springer
Background An accurate understanding of the mechanical response of ligaments is
important for preventing their damage and rupture. To date, ligament mechanical responses …

Dysregulated assembly of elastic fibers in fibulin-5 knockout mice results in a tendon-specific increase in elastic modulus

JD Eekhoff, H Steenbock, IM Berke… - journal of the …, 2021 - Elsevier
Elastic fiber assembly is coordinated in part by fibulin-5, a matricellular protein. When fibulin-
5 is not available to guide elastogenesis, elastin forms into disconnected globules instead of …

Fibrous finite element modeling of the optic nerve head region

MR Islam, F Ji, M Bansal, Y Hua, IA Sigal - Acta Biomaterialia, 2024 - Elsevier
The optic nerve head (ONH) region at the posterior pole of the eye is supported by a fibrous
structure of collagen fiber bundles. Discerning how the fibrous structure determines the …

Theoretical modeling of the mechanical properties of biological fibers and bundles with hierarchical chiral structures

Y Zhang, H Yu, Q Qin, C Qu, J Wang - Acta Mechanica Sinica, 2023 - Springer
Due to the existence of highly ordered hierarchical chiral structures, biological fibers and
bundles such as tendons, ligaments, and climbing tendrils usually have excellent …

Neural network auto‐segmentation of serial‐block‐face scanning electron microscopy images exhibit collagen fibril structural differences with tendon type and health

ET Bloom, CR Sabanayagam… - Journal of …, 2025 - Wiley Online Library
AU‐Net machine learning algorithm was adapted to automatically segment tendon collagen
fibril cross‐sections from serial block face scanning electron microscopy (SBF‐SEM) and …

Evaluation of transverse poroelastic mechanics of tendon using osmotic loading and biphasic mixture finite element modeling

BN Safa, ET Bloom, AH Lee, MH Santare… - Journal of …, 2020 - Elsevier
Tendon's viscoelastic behaviors are important to the tissue mechanical function and cellular
mechanobiology. When loaded in longitudinal tension, tendons often have a large Poisson's …