Dysfunctions of the basal ganglia are associated with a number of neurological and
psychiatric conditions including Parkinson's disease and schizophrenia. Current treatments …

Antipsychotic drugs are extensively prescribed for the treatment of schizophrenia and other
related psychiatric disorders. These drugs produced their action by blocking dopamine (DA) …

Haloperidol is a commonly prescribed antipsychotic drug currently administered as oral and
injectable preparations. This study aimed to prepare haloperidol intranasal miniemulsion …

Introduction Despite a number of medicinally important pharmacological effects, the
therapeutic use of psychostimulants is limited because of abuse potential and psychosis …

The mechanism by which stimulation of somatodendritic and/or postsynaptic 5-
hydroxytryptamine (5-HT, serotonin)-1A receptor could attenuate acute Parkinsonian-like …

Present study was designed to monitor the responsiveness of 5HT (5-Hydroxytryptamine)-
2C receptors following the long-term administration of haloperidol in rats. Effects of m-CPP …

This study evaluates the antiallodynic and antihyperalgesic effects of LMH-2, a new
haloperidol (HAL) analog that acts as sigma-1 receptor (σ1 R) antagonist, in diabetic mice …

Antipsychotic drugs have been shown to modulate immediate early gene (IEG) expression
in rat brain regions that are associated with schizophrenia, which may be directly linked to …

Abstract Effects of coadministration of buspirone were investigated on the time course of
haloperidol-induced extrapyramidal symptoms in rats. Rats treated with haloperidol at a …

Various types of antipsychotics have been developed for the treatment of schizophrenia
since the accidental discovery of the antipsychotic activity of chlorpromazine. Although all …