Synthetic azo-dye, Tartrazine induces neurodevelopmental toxicity via mitochondria-mediated apoptosis in zebrafish embryos

B Haridevamuthu, R Murugan, B Seenivasan… - Journal of Hazardous …, 2024 - Elsevier
Abstract Tartrazine (TZ), or E 102 or C Yellow, is a commonly used azo dye in the food and
dyeing industries. Its excessive usage beyond permissible levels threatens human health …

[HTML][HTML] Neurotoxicity and endocrine disruption caused by polystyrene nanoparticles in zebrafish embryo

M Torres-Ruiz, M de Alba González, M Morales… - Science of The Total …, 2023 - Elsevier
Nanoplastics (NP) are present in aquatic and terrestrial ecosystems. Humans can be
exposed to them through contaminated water, food, air, or personal care products …

DMSO concentrations up to 1% are safe to be used in the zebrafish embryo developmental toxicity assay

J Hoyberghs, C Bars, M Ayuso… - Frontiers in …, 2021 - frontiersin.org
Dimethyl sulfoxide (DMSO) is a popular solvent for developmental toxicity testing of
chemicals and pharmaceuticals in zebrafish embryos. In general, it is recommended to keep …

Modeling human muscular dystrophies in zebrafish: mutant lines, transgenic fluorescent biosensors, and phenotyping assays

C Tesoriero, F Greco, E Cannone, F Ghirotto… - International Journal of …, 2023 - mdpi.com
Muscular dystrophies (MDs) are a heterogeneous group of myopathies characterized by
progressive muscle weakness leading to death from heart or respiratory failure. MDs are …

[HTML][HTML] Adverse effects of bifenthrin exposure on neurobehavior and neurodevelopment in a zebrafish embryo/larvae model

K Eghan, S Lee, D Yoo, CH Kim, WK Kim - Chemosphere, 2023 - Elsevier
Bifenthrin, a third-generation synthetic pyrethroid, is widely used as an agricultural
insecticide. However, it can flow into surface and groundwater, leading to adverse …

Unraveling the mechanisms of perfluorooctanesulfonic acid-induced dopaminergic neurotoxicity and microglial activation in developing zebrafish

A Mahapatra, P Gupta, A Suman, SS Ray… - Science of the Total …, 2023 - Elsevier
Perfluorooctanesulfonic acid (PFOS) is a prevalent, persistent organic pollutant in
environmental matrices, yet its precise mechanism of neurotoxicity remains unclear. This …

New approach methods to improve human health risk assessment of thyroid hormone system disruption–a PARC project

L Ramhøj, M Axelstad, Y Baert… - Frontiers in …, 2023 - frontiersin.org
Current test strategies to identify thyroid hormone (TH) system disruptors are inadequate for
conducting robust chemical risk assessment required for regulation. The tests rely heavily on …

[HTML][HTML] Experimental arena size alters larval zebrafish photolocomotor behaviors and influences bioactivity responses to a model neurostimulant

LM Lovin, KR Scarlett, AN Henke, JL Sims… - Environment …, 2023 - Elsevier
Zebrafish behavior is increasingly common in biomedical and environmental studies of
chemical bioactivity. Multiple experimental arena sizes have been used to measure …

Sorption of PFOS onto polystyrene microplastics potentiates synergistic toxic effects during zebrafish embryogenesis and neurodevelopment

P Gupta, A Mahapatra, B Manna, A Suman, SS Ray… - Chemosphere, 2024 - Elsevier
Microplastics (MPs) have become an emerging anthropogenic pollutant, and their ability to
sorb contaminants potentially enhances the threats to the ecosystem. Only a few studies are …

Integrating morphological, biochemical, behavioural, and molecular approaches to investigate developmental toxicity triggered by tebuthiuron in zebrafish (Danio rerio …

AÁS de Oliveira, LC Vieira, SC Dreossi, DJ Dorta… - Chemosphere, 2023 - Elsevier
Tebuthiuron (TBU), a phenylurea herbicide, is widely applied in agricultural and non-
agricultural soils. Because TBU resists degradation, it can contaminate water and reach the …