Advanced age is associated with defects in all of the cells of the innate immune system,
including numbers, function, and early stages of activation. This review, presents the current …

This review focuses on the effects of estrogens upon the cerebellum, a brain region long
ignored as a site of estrogen action. Highlighted are the diverse effects of estradiol within the …

Close correlations have recently been shown among the late onset complications
encountered in diabetes and aging linked to neurobiological disorders. Aging in females …

Although cardiovascular diseases are less prevalent in premenopausal women than in men,
their occurrence in women increases at the onset of menopause, and the loss of female sex …

Metformin, a biguanide drug commonly used to treat type 2 diabetes, has been noted to
function as a caloric restriction mimetic. Its antidiabetic effect notwithstanding, metformin is …

Estrogen is involved in lipid metabolism. Menopausal women with low estrogen secretion
usually gain weight and develop steatosis associated with abnormal lipid metabolism. A …

Advanced age is a major risk factor for metabolic disorders. Accelerated inflammatory
processes with increased age can contribute to the pathogenesis of metabolic disturbances …

Postmenopausal osteoporosis is one of the most common metabolic diseases in old women,
and supplementing estrogen through bioactive substances is one of the important ways to …

The aim of the study was to assess the age dependence on some physiological and serum
chemistry parameters of male Wistar rats for the estimation of reference values in controlled …

The most energy-requiring organ in the body, the cardiac muscle, relies primarily on
lipoprotein-derived fatty acids. Prenatal loss of cardiac lipoprotein lipase (LPL) leads to …