Mitochondria are organelles that are able to adjust and respond to different stressors and
metabolic needs within a cell, showcasing their plasticity and dynamic nature. These …

The uptake of calcium into and extrusion of calcium from the mitochondrial matrix is a
fundamental biological process that has critical effects on cellular metabolism, signaling …

Besides their role in cell metabolism, mitochondria display many other functions.
Mitochondrial DNA (mtDNA), the own genome of the organelle, plays an important role in …

Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …

Mitochondria are essential organelles with numerous functions in cellular metabolism and
homeostasis. Most of the> 1,000 different mitochondrial proteins are synthesized as …

Biological energy conversion in mitochondria is carried out by the membrane protein
complexes of the respiratory chain and the mitochondrial ATP synthase in the inner …

Mitochondria are dynamic cellular organelles that consistently migrate, fuse, and divide to
modulate their number, size, and shape. In addition, they produce ATP, reactive oxygen …

Introduction: Mitochondria are cellular organelles that perform numerous bioenergetic,
biosynthetic, and regulatory functions and play a central role in iron metabolism …

The protonation state of soluble and membrane-associated macromolecules dictates their
charge, conformation, and functional activity. In addition, protons (H+ or their equivalents) …

The rediscovery and reinterpretation of the Warburg effect in the year 2000 occulted for
almost a decade the key functions exerted by mitochondria in cancer cells. Until recent …