An effective drug-free hydrogel for accelerating the whole healing process of bacteria-infected wounds

Y Cheng, X Liu, F Fan, Y Zhang, M Cao, L Bai… - Biomaterials …, 2025 - pubs.rsc.org
Wound healing is a dynamic and complex process involving hemostasis, inflammation,
fibroblast proliferation, and tissue remodeling. This process is highly susceptible to bacterial …

GITR and TIGIT immunotherapy provokes divergent multicellular responses in the tumor microenvironment of gastrointestinal cancers

A Sathe, C Ayala, X Bai, SM Grimes, B Lee, C Kin… - Genome Medicine, 2023 - Springer
Background Understanding the mechanistic effects of novel immunotherapy agents is critical
to improving their successful clinical translation. These effects need to be studied in …

Performance comparison of high throughput single-cell RNA-Seq platforms in complex tissues

Y Colino-Sanguino, LR de la Fuente, B Gloss… - Heliyon, 2024 - cell.com
Single-cell transcriptomics has emerged as the preferred tool to define cell identity through
the analysis of gene expression signatures. However, there are limited studies that have …

An optimized explant Organoid Method for Preclinical Brain Tumor Research

HM Palethorpe, C Shard, KG Scheer, CP Ryan… - 2024 - papers.ssrn.com
Abstract Treatment for newly diagnosed brain cancer patients has not changed in the last 20
years. Several significant disease obstacles have hampered clinical progress. Among these …