Diagnosis of Clostridium difficile infection: an ongoing conundrum for clinicians and for clinical laboratories

BD Carey-Ann, KC Carroll - Clinical microbiology reviews, 2013 - Am Soc Microbiol
Clostridium difficile is a formidable nosocomial and community-acquired pathogen, causing
clinical presentations ranging from asymptomatic colonization to self-limiting diarrhea to …

Biology of Clostridium difficile: Implications for Epidemiology and Diagnosis

C Karen C, B John G - Annual review of microbiology, 2011 - annualreviews.org
Clostridium difficile is an anaerobic, spore-forming, gram-positive rod that causes a
spectrum of antibiotic-associated colitis through the elaboration of two large clostridial toxins …

Epidemiology of community-associated Clostridium difficile infection, 2009 through 2011

AS Chitnis, SM Holzbauer, RM Belflower… - JAMA internal …, 2013 - jamanetwork.com
Importance Clostridium difficileinfection (CDI) has been increasingly reported among
healthy individuals in the community. Recent data suggest that community-associated CDI …

Changes in Colonic Bile Acid Composition following Fecal Microbiota Transplantation Are Sufficient to Control Clostridium difficile Germination and Growth

AR Weingarden, PI Dosa, E DeWinter, CJ Steer… - PloS one, 2016 - journals.plos.org
Fecal microbiota transplantation (FMT) is a highly effective therapy for recurrent Clostridium
difficile infection (R-CDI), but its mechanisms remain poorly understood. Emerging evidence …

Ursodeoxycholic acid inhibits Clostridium difficile spore germination and vegetative growth, and prevents the recurrence of ileal pouchitis associated with the infection

AR Weingarden, C Chen, N Zhang… - Journal of clinical …, 2016 - journals.lww.com
Background: The restoration of secondary bile metabolism may be the key mechanism for
fecal microbiota transplantation (FMT) in treating recurrent C. difficile infections (RCDI) …

Tests for the diagnosis of Clostridium difficile infection: the next generation

KC Carroll - Anaerobe, 2011 - Elsevier
Clostridium difficile (C. difficile) causes 25–30% of cases of antibiotic associated diarrhea
and most cases of pseudomembranous colitis. Patients presenting with diarrhea after …

A review of Clostridioides [Clostridium] difficile occurrence through the food chain

C Candel-Pérez, G Ros-Berruezo, C Martínez-Graciá - Food microbiology, 2019 - Elsevier
The epidemiology and transmission of Clostridioides difficile, particularly for community-
associated infections, are not completely understood. Although there have been no …

[HTML][HTML] Possible seasonality of Clostridium difficile in retail meat, Canada

A Rodriguez-Palacios, RJ Reid-Smith… - Emerging infectious …, 2009 - ncbi.nlm.nih.gov
We previously reported Clostridium difficile in 20% of retail meat in Canada, which raised
concerns about potential foodborne transmissibility. Here, we studied the genetic diversity of …

Clostridium difficile

SR Curry - Clinics in laboratory medicine, 2010 - pmc.ncbi.nlm.nih.gov
Clostridium difficile infections (CDI) have emerged as one of the principal threats to the
health of hospitalized and immunocompromised patients. Nucleic acid testing for C. difficile …

Diversity of Clostridium difficile in pigs and other animals in Slovenia

J Avbersek, S Janezic, M Pate, M Rupnik, V Zidaric… - Anaerobe, 2009 - Elsevier
A study of Clostridium difficile diversity in pigs, calves and horses in Slovenia was
conducted. A total of 547 samples were collected and C. difficile was isolated from 247/485 …