Prescribed drugs containing nitrogen heterocycles: an overview

MM Heravi, V Zadsirjan - RSC advances, 2020 - pubs.rsc.org
Heteroatoms as well as heterocyclic scaffolds are frequently present as the common cores in
a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all …

Fluoroquinolones hybrid molecules as promising antibacterial agents in the fight against antibacterial resistance

IA Lungu, OL Moldovan, V Biriș, A Rusu - Pharmaceutics, 2022 - mdpi.com
The emergence of bacterial resistance has motivated researchers to discover new
antibacterial agents. Nowadays, fluoroquinolones keep their status as one of the essential …

Efficient and synergistic degradation of fluoroquinolones by bacteria and microalgae: Design of environmentally friendly substitutes, risk regulation and mechanism …

R Fu, X Li, Y Zhao, Q Pu, Y Li, W Gu - Journal of Hazardous Materials, 2022 - Elsevier
Fluoroquinolones (FQs) are widely used as antimicrobial agents, and their
nonbiodegradable in sewage has become an increasingly concerning. High-biochemical …

An electrochemical sensor based on MnO2/ZnO composites for the detection of ciprofloxacin in honey

S Zhang, S Yu, X Wang, Y Zhang, Z Yue, C Li… - Microchemical Journal, 2023 - Elsevier
Long-term consumption of honey containing ciprofloxacin (CIP) residues may harm human
health. It is important to establish a sensitive and rapid CIP detection method. This study …

Novel triazole bridged quinoline-anthracene derivatives: synthesis, characterization, molecular docking, evaluation of electronic and enzyme inhibitory properties

A Gümüş, N Sadeghian, M Sadeghi… - Journal of …, 2025 - Taylor & Francis
Two novel quinoline-anthracene conjugates comprising styrylquinoline and anthracene
moieties linked by triazole bridges were designed and synthesized in good yields. These …

Modification of 7-piperazinylquinolone antibacterials to promising anticancer lead compounds: Synthesis and in vitro studies

H Ahadi, S Emami - European Journal of Medicinal Chemistry, 2020 - Elsevier
Amongst the fluoroquinolone antibacterials, the 7-piperazinyl containing chemotypes such
as norfloxacin, enoxacin, ciprofloxacin, pefloxacin, lomefloxacin, enrofloxacin, ofloxacin …

Antibacterial activity and physicochemical characterization of calcium-aluminium-ciprofloxacin-layered double hydroxide

ML Jadam, SAS Mohamad, HM Zaki, Z Jubri… - Journal of Drug Delivery …, 2021 - Elsevier
A fluoroquinolone antibacterial drug, ciprofloxacin (CPX) was successfully intercalated into
calcium–aluminium-layered double hydroxide (CAL) with a molar ratio of 3: 1 (Ca: Al) by …

[PDF][PDF] Design, synthesis, in-silico study and anticancer potential of novel n-4-piperazinyl-ciprofloxacin-aniline hybrids

R Akhtar, AF Zahoor, A Rasul, M Ahmad… - Pak. J. Pharm …, 2019 - researchgate.net
Synthesis and characterization of novel structural hybrids of ciprofloxacin linked with a
variety of anilides have been described in this paper. Antitumor activity of these derivatives …

Design, synthesis, molecular docking study, and antibacterial evaluation of some new fluoroquinolone analogues bearing a quinazolinone moiety

M Norouzbahari, S Salarinejad, M Güran… - DARU Journal of …, 2020 - Springer
Background Increasing bacterial resistance to quinolones is concerning. Hence, the
development of novel quinolones by chemical modifications to overcome quinolone …

Synthesis and Biological Evaluation of New Isatin‐Based QACs with High Antimicrobial Potency

AV Bogdanov, IF Zaripova, AD Voloshina… - …, 2019 - Wiley Online Library
A simple and easy condensation reaction of aryl‐or N‐substituted isatins with Girard's
reagents P and T was found to be useful in obtaining of water‐soluble isatin‐based …