Serum albumin, a natural ligand carrier that is highly concentrated and long-circulating in
the blood, has shown remarkable promise as a carrier for anti-cancer agents. Albumin is …

The RNA interference (RNAi) pathway possesses immense potential in silencing any gene
in human cells. Small interfering RNA (siRNA) can efficiently trigger RNAi silencing of …

Small interfering RNAs (siRNAs) are a new class of promising therapeutic molecules that
can be used for sequence-specific downregulation of disease-causing genes. However …

Small interfering RNAs (siRNAs) acting via RNA interference mechanisms are able to
recognize a homologous mRNA sequence in the cell and induce its degradation. The main …

Short interfering RNAs (siRNA) are a powerful class of genetic medicines whose clinical
translation can be hindered by their suboptimal delivery properties in vivo. Here, we provide …

Oligonucleotide-based agents have the potential to treat or cure almost any disease, and
are one of the key therapeutic drug classes of the future. Bioconjugated oligonucleotides, a …

Thanks to their abilities to modulate the expression of virtually any genes, RNA therapeutics
have attracted considerable research efforts. Among the strategies focusing on nucleic acid …

Globally, cancer is amongst the most deadly diseases due to the low efficiency of the
conventional and obsolete chemotherapeutic methodologies and their many downsides …

Extracellular vesicles (EVs) are membrane vesicles released into the extracellular milieu by
cells of various origins. They contain different biological cargoes, protecting them from …

RNA interference (RNAi) is a major cellular mechanism regulating gene expression in which
short double-stranded RNA molecules called small interfering RNA (siRNA) mediate …