Thrombus structural composition in cardiovascular disease
Thrombosis is a major complication of cardiovascular disease, leading to myocardial
infarction, acute ischemic stroke, or venous thromboembolism. Thrombosis occurs when a …
infarction, acute ischemic stroke, or venous thromboembolism. Thrombosis occurs when a …
Fibrin formation, structure and properties
JW Weisel, RI Litvinov - Fibrous proteins: structures and mechanisms, 2017 - Springer
Fibrinogen and fibrin are essential for hemostasis and are major factors in thrombosis,
wound healing, and several other biological functions and pathological conditions. The X …
wound healing, and several other biological functions and pathological conditions. The X …
The distinctive structure and composition of arterial and venous thrombi and pulmonary emboli
IN Chernysh, C Nagaswami, S Kosolapova… - Scientific reports, 2020 - nature.com
Although arterial and venous thromboembolic disorders are among the most frequent
causes of mortality and morbidity, there has been little description of how the composition of …
causes of mortality and morbidity, there has been little description of how the composition of …
[HTML][HTML] Red blood cells: the forgotten player in hemostasis and thrombosis
JW Weisel, RI Litvinov - Journal of Thrombosis and Haemostasis, 2019 - Elsevier
New evidence has stirred up a long‐standing but undeservedly forgotten interest in the role
of erythrocytes, or red blood cells (RBCs), in blood clotting and its disorders. This review …
of erythrocytes, or red blood cells (RBCs), in blood clotting and its disorders. This review …
Thrombosis formation on atherosclerotic lesions and plaque rupture
L Badimon, G Vilahur - Journal of internal medicine, 2014 - Wiley Online Library
Atherosclerosis is a silent chronic vascular pathology that is the cause of the majority of
cardiovascular ischaemic events. The evolution of vascular disease involves a combination …
cardiovascular ischaemic events. The evolution of vascular disease involves a combination …
Mechanisms of fibrin polymerization and clinical implications
JW Weisel, RI Litvinov - Blood, The Journal of the American …, 2013 - ashpublications.org
Research on all stages of fibrin polymerization, using a variety of approaches including
naturally occurring and recombinant variants of fibrinogen, x-ray crystallography, electron …
naturally occurring and recombinant variants of fibrinogen, x-ray crystallography, electron …
Clot contraction: compression of erythrocytes into tightly packed polyhedra and redistribution of platelets and fibrin
DB Cines, T Lebedeva, C Nagaswami… - Blood, The Journal …, 2014 - ashpublications.org
Contraction of blood clots is necessary for hemostasis and wound healing and to restore
flow past obstructive thrombi, but little is known about the structure of contracted clots or the …
flow past obstructive thrombi, but little is known about the structure of contracted clots or the …
Neutrophil extracellular traps and endothelial dysfunction in atherosclerosis and thrombosis
H Qi, S Yang, L Zhang - Frontiers in immunology, 2017 - frontiersin.org
Cardiovascular diseases are a leading cause of mortality and morbidity worldwide.
Neutrophils are a component of the innate immune system which protect against pathogen …
Neutrophils are a component of the innate immune system which protect against pathogen …
[HTML][HTML] Pathology of coronary atherosclerosis and thrombosis
F Otsuka, S Yasuda, T Noguchi… - … diagnosis and therapy, 2016 - ncbi.nlm.nih.gov
The process of early atherosclerotic plaque progression is characterized by the
development of pathologic intimal thickening (PIT) with lipid pool that may transform into the …
development of pathologic intimal thickening (PIT) with lipid pool that may transform into the …
Targeting myeloid cell coagulation signaling blocks MAP kinase/TGF-β1–driven fibrotic remodeling in ischemic heart failure
V Garlapati, M Molitor, T Michna… - The Journal of …, 2023 - Am Soc Clin Investig
Despite major advances in acute interventions for myocardial infarction (MI), adverse
cardiac remodeling and excess fibrosis after MI causing ischemic heart failure (IHF) remain …
cardiac remodeling and excess fibrosis after MI causing ischemic heart failure (IHF) remain …