Microbiota-gut brain axis involvement in neuropsychiatric disorders

LF Iannone, A Preda, HM Blottière… - Expert review of …, 2019 - Taylor & Francis
Introduction: The microbiota-gut brain (MGB) axis is the bidirectional communication
between the intestinal microbiota and the brain. An increasing body of preclinical and …

Wearable devices in clinical trials: hype and hypothesis

ES Izmailova, JA Wagner… - Clinical Pharmacology & …, 2018 - Wiley Online Library
The development of innovative wearable technologies has raised great interest in new
means of data collection in healthcare and biopharmaceutical research and development …

Evaluation of smartphone‐based testing to generate exploratory outcome measures in a phase 1 Parkinson's disease clinical trial

F Lipsmeier, KI Taylor, T Kilchenmann… - Movement …, 2018 - Wiley Online Library
Background: Ubiquitous digital technologies such as smartphone sensors promise to
fundamentally change biomedical research and treatment monitoring in neurological …

[HTML][HTML] The use of wearable activity trackers among older adults: focus group study of tracker perceptions, motivators, and barriers in the maintenance stage of …

A Kononova, L Li, K Kamp, M Bowen… - JMIR mHealth and …, 2019 - mhealth.jmir.org
Background: Wearable activity trackers offer the opportunity to increase physical activity
through continuous monitoring. Viewing tracker use as a beneficial health behavior, we …

Physical therapy and occupational therapy in Parkinson's disease

DLM Radder, IH Sturkenboom… - International Journal …, 2017 - Taylor & Francis
Current medical management is only partially effective in controlling the symptoms of
Parkinson's disease. As part of comprehensive multidisciplinary care, physical therapy and …

Feasibility of large-scale deployment of multiple wearable sensors in Parkinson's disease

AL Silva de Lima, T Hahn, LJW Evers, NM De Vries… - PloS one, 2017 - journals.plos.org
Wearable devices can capture objective day-to-day data about Parkinson's Disease (PD).
This study aims to assess the feasibility of implementing wearable technology to collect data …

Outcome measures based on digital health technology sensor data: data-and patient-centric approaches

KI Taylor, H Staunton, F Lipsmeier, D Nobbs… - NPJ digital …, 2020 - nature.com
Digital health technology tools (DHTT) are technologies such as apps, smartphones, and
wearables that remotely acquire health-related information from individuals. They have the …

A deep learning approach for parkinson's disease severity assessment

T Aşuroğlu, H Oğul - Health and Technology, 2022 - Springer
Abstract Purpose Parkinson's Disease comes on top among neurodegenerative diseases
affecting 10 million worldwide. To detect Parkinson's Disease in a prior state, gait analysis is …

Digitally enabled, patient‐centric clinical trials: shifting the drug development paradigm

MF Dockendorf, BJ Hansen… - Clinical and …, 2021 - Wiley Online Library
The rapidly advancing field of digital health technologies provides a great opportunity to
radically transform the way clinical trials are conducted and to shift the clinical trial paradigm …

Clinical assessments in Parkinson's disease: scales and monitoring

R Bhidayasiri, P Martinez-Martin - International review of neurobiology, 2017 - Elsevier
Measurement of disease state is essential in both clinical practice and research in order to
assess the severity and progression of a patient's disease status, effect of treatment, and …