Pyroptosis in health and disease: mechanisms, regulation and clinical perspective

Y Liu, R Pan, Y Ouyang, W Gu, T Xiao… - Signal transduction and …, 2024 - nature.com
Pyroptosis is a type of programmed cell death characterized by cell swelling and osmotic
lysis, resulting in cytomembrane rupture and release of immunostimulatory components …

Exploring ncRNA-mediated pathways in sepsis-induced pyroptosis

AA Bhat, Y Riadi, M Afzal, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Sepsis, a potentially fatal illness caused by an improper host response to infection, remains
a serious problem in the world of healthcare. In recent years, the role of ncRNA has …

[HTML][HTML] Targeting catalase in cancer

C Glorieux, PB Calderon - Redox Biology, 2024 - Elsevier
Healthy cells have developed a sophisticated network of antioxidant molecules to prevent
the toxic accumulation of reactive oxygen species (ROS) generated by diverse …

The role of ncRNAs‐mediated pyroptosis in diabetes and its vascular complications

X Feng, X Yang, Y Zhong… - Cell Biochemistry and …, 2024 - Wiley Online Library
Over the past decade, the prevalence of diabetes has increased significantly worldwide,
leading to an increase in vascular complications of diabetes (VCD), such as diabetic …

The lncRNA MALAT1 is upregulated in urine of type 1 diabetes mellitus patients with diabetic kidney disease

C Dieter, NE Lemos, E Girardi, DT Ramos… - … and Molecular Biology, 2023 - SciELO Brasil
Long non-coding RNAs (lncRNAs) are RNAs with> 200 nucleotides that are unable to
encode proteins and are involved in gene expression regulation. LncRNAs have a key role …

Exploring potential targets for natural product therapy of DN: the role of SUMOylation

J Wang, R Zhang, C Wu, L Wang, P Liu… - Frontiers in …, 2024 - frontiersin.org
Diabetic nephropathy (DN) is a common and serious micro-vascular complication of
diabetes and a leading cause of end-stage renal disease globally. This disease primarily …

Research progress of non-coding RNA regulating the role of PANoptosis in diabetes mellitus and its complications

G Han, K Hu, T Luo, W Wang, D Zhang, L Ouyang… - Apoptosis, 2025 - Springer
Diabetes is a chronic metabolic disease that is endemic worldwide and is characterized by
persistent hyperglycemia accompanied by multiple severe complications, including …

The role of long non‐coding RNAs in the development of diabetic kidney disease and the involved clinical application

Q Hou, B Yi - Diabetes/Metabolism Research and Reviews, 2024 - Wiley Online Library
Diabetic kidney disease (DKD), one of the common microvascular complications of diabetes,
is increasing in prevalence worldwide and can lead to End‐stage renal disease. However …

The emerging role of MALAT1 lncRNA in diabetic nephropathy: based on the review of the literature and bioinformatic analysis

S Nikooei, E Azadifar, B Alipoor - Acta Biochimica …, 2023 - publish.kne-publishing.com
Previous studies have found that the metastasis-associated lung adenocarcinoma transcript
1 (MALAT1) exerts its biological effects on the progression of diabetic nephropathy by …

MALAT1 promotes colonic epithelial cell apoptosis and pyroptosis by sponging miR-22-3p to enhance NLRP3 expression

R Yan, X Liang, J Hu - PeerJ, 2024 - peerj.com
Background Colonic epithelial cell apoptosis and pyroptosis had a close relationship with
the pathological progression of ulcerative colitis (UC). LncRNA play a crucial role in the …