With the development of modern high-throughput omic measurement platforms, it has
become essential for biomedical studies to undertake an integrative (combined) approach to …

Parkinson disease (PD) is a progressive disorder characterized by dopaminergic
neurodegeneration in the brain. The development of parkinsonism is preceded by a long …

Importance Imaging biomarkers in Parkinson disease (PD) are increasingly important for
monitoring progression in clinical trials and also have the potential to improve clinical care …

The patients' vocal Parkinson's disease (PD) changes could be identified early on, allowing
for management before physically incapacitating symptoms appear. In this work, static as …

Tauopathies are classified according to whether tau deposits predominantly contain tau
isoforms with three or four repeats of the microtubule-binding domain. Those in which four …

Abstract Background The recent International Parkinson and Movement Disorder Society
diagnostic criteria for multiple system atrophy (MDS‐MSA) have been developed to improve …

The recent validation of the α-synuclein seed amplification assay as a biomarker with high
sensitivity and specificity for the diagnosis of Parkinson's disease has formed the backbone …

Background Machine learning algorithms using magnetic resonance imaging (MRI) data
can accurately discriminate parkinsonian syndromes. Validation in patients recruited in …

Purpose Free‐water elimination DTI (FWE‐DTI) has been used widely to distinguish
increases of free‐water partial‐volume effects from tissue's diffusion in healthy aging and …

Background Rapid advances in neuroimaging technologies in the exploration of the living
human brain also apply to movement disorders. However, the accurate diagnosis of …