The rapid development of drug nanocarriers has benefited from the surface hydrophilic
polymers of particles, which has improved the pharmacokinetics of the drugs. Polyethylene …

Infectious diseases are a major driver of morbidity and mortality globally. Treatment of
malaria, tuberculosis and human immunodeficiency virus infection are particularly …

Despite the clinical introduction of an increasing number of polyethylene glycol (PEG)-
conjugated substances, PEG has been named as the cause of an unexpected immunogenic …

A significant proportion of recently approved drug molecules possess poor aqueous
solubility which further restrains their desired bioavailability. Poor aqueous solubility of these …

Despite the fact that we live in an era of advanced technology and innovation, infectious
diseases, like malaria, continue to be one of the greatest health challenges worldwide. The …

Malaria is an infectious disease that mainly affects children and pregnant women from
tropical countries. The mortality rate of people infected with malaria per year is enormous …

The accelerated blood clearance (ABC) phenomenon accounts for the rapid systemic
clearance of PEGylated nanocarriers upon repeated administrations. IgM production against …

The present investigation involved preparation of hydrogel nanoparticles using a
combination of hydroxyl propyl methyl cellulose and polyvinyl pyrrolidone. The objective …

Response surface methodology (RSM) using the central composite rotatable design
(CCRD) model was used to optimize formulations of dihydroartemisinin nanostructured lipid …

Systemic infections is one of the major causes of mortality worldwide, and a shortage of drug
approaches applied for the rapid and necessary treatment contribute to increase the levels …