Epstein–Barr virus latent genes

MS Kang, E Kieff - Experimental & molecular medicine, 2015 - nature.com
Abstract Latent Epstein–Barr virus (EBV) infection has a substantial role in causing many
human disorders. The persistence of these viral genomes in all malignant cells, yet with the …

Large-scale transfection of mammalian cells for the fast production of recombinant protein

PL Pham, A Kamen, Y Durocher - Molecular biotechnology, 2006 - Springer
Recombinant proteins (r-proteins) are increasingly important in fundamental research and
for clinical applications. As many of these r-proteins are of human or animal origin, cultivated …

Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7

MN Holowaty, M Zeghouf, H Wu, J Tellam… - Journal of Biological …, 2003 - ASBMB
The Epstein-Barr nuclear antigen-1 (EBNA1) protein of Epstein-Barr virus is important for the
replication, segregation, and transcriptional activation of latent Epstein-Barr virus genomes; …

Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen 1 Mediates Episome Persistence through cis-Acting Terminal Repeat (TR) Sequence …

ME Ballestas, KM Kaye - Journal of virology, 2001 - Am Soc Microbiol
ABSTRACT Kaposi's sarcoma (KS)-associated herpesvirus (KSHV)(also known as human
herpesvirus 8) latently infects KS tumors, primary effusion lymphomas (PELs), and PEL cell …

Identification of potential inhibitors against Epstein–Barr virus nuclear antigen 1 (EBNA1): An insight from docking and molecular dynamic simulations

S Jakhmola, NA Jonniya, MF Sk, A Rani… - ACS Chemical …, 2021 - ACS Publications
Epstein–Barr virus (EBV), a known tumorigenic virus, is associated with various
neuropathies, including multiple sclerosis (MS). However, there is no anti-EBV FDA …

Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies

N Sivachandran, F Sarkari, L Frappier - PLoS pathogens, 2008 - journals.plos.org
Latent Epstein-Barr virus (EBV) infection is strongly associated with several cancers,
including nasopharyngeal carcinoma (NPC), a tumor that is endemic in several parts of the …

The hide-and-seek game of the oncogenic Epstein-Barr virus-encoded EBNA1 protein with the immune system: An RNA G-quadruplex tale

VT Dinh, N Loaëc, A Quillévéré, R Le Sénéchal… - Biochimie, 2023 - Elsevier
Abstract The Epstein-Barr virus (EBV) is the first oncogenic virus described in human. EBV
infects more than 90% of the human population worldwide, but most EBV infections are …

Ebna1

L Frappier - Epstein Barr Virus Volume 2: One Herpes Virus: Many …, 2015 - Springer
Epstein–Barr nuclear antigen 1 (EBNA1) plays multiple important roles in EBV latent
infection and has also been shown to impact EBV lytic infection. EBNA1 is required for the …

EBNA1-mediated recruitment of a histone H2B deubiquitylating complex to the Epstein-Barr virus latent origin of DNA replication

F Sarkari, T Sanchez-Alcaraz, S Wang… - PLoS …, 2009 - journals.plos.org
The EBNA1 protein of Epstein-Barr virus (EBV) plays essential roles in enabling the
replication and persistence of EBV genomes in latently infected cells and activating EBV …

[HTML][HTML] Unraveling the Aurora kinase A and Epstein-Barr nuclear antigen 1 axis in Epstein Barr virus associated gastric cancer

N Varshney, S Murmu, B Baral, D Kashyap, S Singh… - Virology, 2023 - Elsevier
Aurora kinase A (AURKA) is one of the crucial cell cycle regulators associated with gastric
cancer. Here, we explored Epstein Barr Virus-induced gastric cancer progression through …