Delivery of genetic information to the interior of target cells in vivo has been a major
challenge facing gene therapies. This barrier is now being overcome, owing in part to …

Abbreviations: PA. phosphalidic acid:;'C, phosphatidylcholine: PE.
phosphatidylethanolamine: PG, phosphatidylglycerol: PS, phosphatidylscrine: E. elaidoyl: L …

The application of cationic liposome reagents has advanced DNA and mRNA transfection
research in vitro, and data are accumulating which show their utility for in vivo gene transfer …

To understand how DNA is released from cationic liposome/DNA complexes in cells, we
investigated which biomolecules mediate release of DNA from a complex with cationic …

The mechanism whereby cationic lipids destabilize cell membranes to facilitate the
intracellular delivery of macromolecules such as plasmid DNA or antisense oligonucleotides …

Cationic lipids are widely used for gene transfer in vitro and show promise as a vector for in
vivo gene therapy applications. However, there is limited understanding of the cellular and …

We propose a mechanism for oligonucleotide (ODN) release from cationic lipid complexes
in cells that accounts for various observations on cationic lipid-nucleic acid-cell interactions …

This volume provides a single-source of reviews for all the important colloidal drug delivery
systems, including nanoparticles, liposomes, niosomes, microemulsions and ointments …

Efficient extracellular vesicle (EV) enrichment and timely internal RNA detection for cancer
diagnostics are highly desirable and remain a challenge. Here, we report a rapid EV …

Although the possibility of targeting drugs to specific tissues and cells, as well as facilitating
their uptake and cytoplasmic delivery has rendered liposomes a versatile drug carrier …