Over the past few decades, gene therapy has gained immense importance in medical
research as a promising treatment strategy for diseases such as cancer, AIDS, Alzheimer's …

Nucleic acids carry the building plans of living systems. As such, they can be exploited to
make cells produce a desired protein, or to shut down the expression of endogenous genes …

Recent study showed that mesenchymal stem cells (MSC) could inhibit apoptosis of
endothelial cells in hypoxic condition, increase their survival, and stimulate the …

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Because
of significant changes in their expression in cancer, miRNAs are believed to be key factors in …

Besides its broad application in research and biotechnology, genome editing (GE) has great
potential for clinical gene therapy, but delivery of GE tools remains a bottleneck. Whereas …

Gene delivery as a promising and valid tool has been used for treating many serious
diseases that conventional drug therapies cannot cure. Due to the advancement of physical …

A significant number of clinical trials have been undertaken to explore the use of
mesenchymal stem cells (MSCs) for the treatment of several diseases such as Crohn's …

The possible different therapeutic efficacy of human mesenchymal stem cells (hMSC)
derived from umbilical cord blood (CB), adipose tissue (AT) or bone marrow (BM) for the …

Magnetic resonance imaging (MRI) allows for an accurate assessment of both functional
and structural cardiac parameters, and thereby appropriate diagnosis and validation of …

This study assessed the concept of whether delivery of magnetic nanobeads
(MNBs)/adenoviral vectors (Ad)–encoded hVEGF gene (AdhVEGF) could regenerate …