Intrinsic and extrinsic pathways of apoptosis: Role in cancer development and prognosis
Apoptosis, also named programmed cell death, is a fundament process required for
morphogenetic homeostasis during early development and in pathophysiological …
morphogenetic homeostasis during early development and in pathophysiological …
Regulatory role of apoptotic and inflammasome related proteins and their possible functional aspect in thiram associated tibial dyschondroplasia of poultry
MFA Kulyar, W Yao, Q Mo, Y Ding, Y Zhang, J Gao, K Li… - Animals, 2022 - mdpi.com
Simple Summary Tibial dyschondroplasia (TD) is a metabolic disorder that impairs bony and
cartilage processes. It is common in broilers due to the consumption of thiram, especially in …
cartilage processes. It is common in broilers due to the consumption of thiram, especially in …
SAHA and EGCG promote apoptosis in triple-negative breast cancer cells, possibly through the modulation of cIAP2
KL Steed, HR Jordan, TO Tollefsbol - Anticancer research, 2020 - ar.iiarjournals.org
Background/Aim: Inhibition of apoptosis is one of the hallmarks of cancer, and anti-apoptotic
genes are often targets of genetic and epigenetic alterations. Cellular inhibitor of apoptosis 2 …
genes are often targets of genetic and epigenetic alterations. Cellular inhibitor of apoptosis 2 …
BCL (X) L and BCL2 increase the metabolic fitness of breast cancer cells: a single-cell imaging study
F Lucantoni, M Salvucci, H Düssmann… - Cell Death & …, 2021 - nature.com
The BCL2 family of proteins regulate apoptosis by controlling mitochondrial outer membrane
permeability. However, the effects on mitochondrial structure and bioenergetics have also …
permeability. However, the effects on mitochondrial structure and bioenergetics have also …
[HTML][HTML] Bioinformatics analysis of BIRC5 in human cancers
HB Ye, BJ Ma, GQ Meng, S Tao, Y Wang… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background An inhibitor of apoptosis (IAP) family member, baculoviral IAP repeat containing
five (BIRC5) plays an important role in the occurrence and development of tumors. However …
five (BIRC5) plays an important role in the occurrence and development of tumors. However …
Downregulation of Diacylglycerol kinase zeta (DGKZ) suppresses tumorigenesis and progression of cervical cancer by facilitating cell apoptosis and cell cycle arrest
K Liu, B Xue, G Bai, W Zhang - Bioengineered, 2021 - Taylor & Francis
Diacylglycerol kinase zeta (DGKZ) participates in cancer progression. Here, the current work
aims to identify the functional role of DGKZ in cervical cancer (CC). DGKZ expression in …
aims to identify the functional role of DGKZ in cervical cancer (CC). DGKZ expression in …
Construction and validation of a prognostic risk model for breast cancer based on protein expression
B Huang, X Zhang, Q Cao, J Chen, C Lin, T Xiang… - BMC Medical …, 2022 - Springer
Breast cancer (BRCA) is the primary cause of mortality among females globally. The
combination of advanced genomic analysis with proteomics characterization to construct a …
combination of advanced genomic analysis with proteomics characterization to construct a …
[HTML][HTML] BCL (X) L and BCL2 increase mitochondrial dynamics in breast cancer cell: Evidence from functional and genetic studies
F Lucantoni, M Salvucci, H Dussmann… - Biochimica et Biophysica …, 2021 - Elsevier
BCL2 family proteins are important regulators of mitochondrial outer membrane
permeabilization (MOMP). In recent years, BCL2 family proteins have also been linked to the …
permeabilization (MOMP). In recent years, BCL2 family proteins have also been linked to the …
Targeting NAD Metabolism: Rational Design, Synthesis and In Vitro Evaluation of NAMPT/PARP1 Dual-Target Inhibitors as Anti-Breast Cancer Agents
Y Li, X Kong, X Chu, H Fu, X Feng, C Zhao, Y Deng… - Molecules, 2024 - mdpi.com
The malignancy of breast cancer poses a global challenge, with existing treatments often
falling short of desired efficacy. Extensive research has underscored the effectiveness of …
falling short of desired efficacy. Extensive research has underscored the effectiveness of …
Changing the Landscape of Solid Tumor Therapy from Apoptosis-Promoting to Apoptosis-Inhibiting Strategies
R Mirzayans - Current Issues in Molecular Biology, 2024 - mdpi.com
The many limitations of implementing anticancer strategies under the term “precision
oncology” have been extensively discussed. While some authors propose promising future …
oncology” have been extensively discussed. While some authors propose promising future …