In rodents, the removal of the olfactory bulbs (OBs), ie olfactory bulbectomy (OBX), results in
numerous alterations in neurotransmitter, endocrine and immune systems, as well as …

Olfactory bulbectomy (OBX), the surgical removal of the olfactory bulbs, lead, both in mice
and rats, to a specific set of behavioral changes in social behavior, cognitive function and …

During the last twenty years, molecular genetic investigations of Alzheimer's disease (AD)
have significantly broadened our knowledge of basic mechanisms of this disorder. However …

People who have developed a good sense of smell could experience much more happiness
and pleasure, which would trigger a discussion that olfactory disorder might correlate with …

Objective The aim of our study was to test whether ketamine produces an antidepressant
effect in animal model of olfactory bulbectomy and assess the role of mammalian target of …

I. введение. II. Молекулярные основы патогенеза болезни Альцгеймера. III. Процесс
образования бета-амилоида. IV. Основные поло жения амилоидной гипотезы. V …

Compensatory/adaptive mechanisms in the brain are hypothesized to be involved in its
protection from the Alzheimer's disease (AD) progression. These mechanisms are activated …

Olfactory bulbectomy (OBX) in rodents induces a wide spectrum of functional disturbances,
including behavioral, neurochemical, and neuromorphological alterations. We have …

Activation of receptor for advanced glycation end products (RAGE) plays an essential role in
the development of Alzheimer's disease (AD). It is known that the soluble isoform of the …

Bilateral olfactory bulbectomy (OBX) has been used as an animal model for major
depression that results in behavioral, neurochemical, and neuroendocrinological changes …