Both KCC3b and KCC3a seem to be needed for maintaining cell volume during enhanced
inward cotransport of Na-glucose in proximal tubule and Na-HCO 3 in intercalated cells. In …

Dietary potassium deficiency causes stimulation of sodium reabsorption leading to an
increased risk in blood pressure elevation. The distal convoluted tubule (DCT) is the main …

Aim Increasing the dietary intake of K+ in the setting of a high salt intake promotes renal Na+
excretion even though K+ concurrently enhances the secretion of aldosterone, the most …

Background: Losing or donating a kidney is associated with risks of developing
hypertension and albuminuria. Few studies address mechanisms or interventions. We …

Klotho regulates many pathways in the aging process, but it remains unclear how it is
physiologically regulated. Because Klotho is synthesized, cleaved, and released from the …

The maintenance of fluid and electrolyte homeostasis by the kidney requires proper folding
and trafficking of ion channels and transporters in kidney epithelia. Each of these processes …

The susceptibility of patients with chronic kidney disease to develop postprandial
hyperkalemia suggests alterations in normal kidney sodium (Na+) and potassium (K+) …

Maintaining acid–base homeostasis is critical for normal physiological function. The kidneys
are essential for regulating acid–base homeostasis through maintaining systemic …

Plasma K+ level is tightly maintained within a narrow range (3.5–5.0 mM) by complex
physiological mechanisms involving coordination of K+ storage occurring mainly in skeletal …

ABSTRACT Objectives We aimed to:(1) explore the effect of oral potassium supplementation
on urinary potassium excretion, and (2) evaluate the value of urinary potassium-related …