Flow cytometry (FCM) offers a multiparametric technology capable of characterizing single
extracellular vesicles (EVs). However, most flow cytometers are designed to detect cells …

Background Our body fluids contain a multitude of cell-derived vesicles, secreted by most
cell types, commonly referred to as extracellular vesicles. They have attracted considerable …

Background Enumeration of extracellular vesicles has clinical potential as a biomarker for
disease. In biological samples, the smallest and largest vesicles typically differ 25‐fold in …

Essentials• Platelet extracellular vesicles (EVs) concentrations measured by flow cytometers
are incomparable.• A model is applied to convert ambiguous scatter units to EV diameter in …

Cell‐derived or extracellular vesicles, including microparticles and exosomes, are
abundantly present in body fluids such as blood. Although such vesicles have gained strong …

Academic and industrial groups worldwide have reported technological advances in
exosome-based cancer diagnosis and prognosis. However, the potential translation of these …

The refractive index (RI) dictates interaction between light and nanoparticles and therefore is
important to health, environmental, and materials sciences. Using nanoparticle tracking …

Introduction Optical techniques are routinely used to size and count extracellular vesicles
(EV). For comparison of data from different methods and laboratories, suitable calibrators …

Essentials• The clinical enumeration of microparticles (MPs) is hampered by a lack of
standardization.• A new strategy to standardize MP counts by flow cytometry was evaluated …

Abstract Extracellular Vesicles (EVs) are potent bio-activators and inter-cellular
communicators that play an important role in both health and disease. It is for this reason …