Meiosis is the cellular program that underlies gamete formation. For this program,
crossovers between homologous chromosomes play an essential mechanical role to ensure …

Three waves of H2AX phosphorylation (γH2AX) have been observed in male meiotic
prophase I: the first is ATM-dependent and occurs at leptonema, while the second and third …

Meiosis is the foundation of sexual reproduction, and crossover recombination is one
hallmark of meiosis. Crossovers establish the physical connections between homolog …

We previously demonstrated that the effects of diethylhexyl phthalate (DEHP) alter
reproduction function on male mice. Immature male mice were treated daily with DEHP from …

The synaptonemal complex (SC) is a proteinaceous scaffold required for synapsis and
recombination between homologous chromosomes during meiosis. Although the SC has …

For the first time in the domestic pig, meiotic recombination along the 18 porcine autosomes
was directly studied by immunolocalization of MLH1 protein. In total, 7,848 synaptonemal …

Reciprocal translocation is one of the most common structural chromosomal rearrangements
in human beings; it is widely recognized to be associated with male infertility. This …

Individuals carrying balanced constitutional reciprocal translocations generally have a
normal phenotype, but often present reproductive disorders. The aim of our research was to …

Meiotic recombination in the Japanese quail was directly studied by immunolocalization of
mutL homolog 1 (MLH1), a mismatch repair protein of mature recombination nodules. In …

Spermatocyte spreading and immunostaining were applied to detect meiotic prophase I
progression, homologous chromosome pairing, synapsis and recombination in an …