Interaction between roxarsone, an organic arsenic compound, with humic substances in the soil simulating environmental conditions
ALA Nascimento, IM Figueiredo, WG Botero… - Chemosphere, 2023 - Elsevier
In environmental systems, the soil is a principal route of contamination by various potentially
toxic species. Roxarsone (RX) is an arsenic (V) organic compound used to treat parasitic …
toxic species. Roxarsone (RX) is an arsenic (V) organic compound used to treat parasitic …
Supramolecular interaction of transition metal complexes with albumins and DNA: Spectroscopic methods of estimation of binding parameters
PА Galkina, МА Proskurnin - Applied Organometallic …, 2018 - Wiley Online Library
Binding parameters of metal complexes with albumins and DNA since the middle of 1990s
are considered and summarized. The most widespread spectroscopic methods of estimation …
are considered and summarized. The most widespread spectroscopic methods of estimation …
In vitro and in silico assessment of antitumor properties and biomolecular binding studies for two new complexes based on NiII bearing k2N, S-donor ligands
RL Farias, AMR Polez, DES Silva, RD Zanetti… - Materials Science and …, 2021 - Elsevier
This work deals with two new molecule-based materials, namely Ni II-complexes of general
formulae [Ni (L1) 2](Ni1) and [Ni (L2) 2](Ni2), where L1= trans-cinnamaldehyde-N (4)-methyl …
formulae [Ni (L1) 2](Ni1) and [Ni (L2) 2](Ni2), where L1= trans-cinnamaldehyde-N (4)-methyl …
Influence of diimine bidentate ligand in the nitrosyl and nitro terpyridine ruthenium complex on the HSA/DNA interaction and antiviral activity
NC Bessas, EC de Souza Arantes, NM Cassani… - Nitric Oxide, 2024 - Elsevier
Nitric oxide (NO) acts in different physiological processes, such as blood pressure control,
antiparasitic activities, neurotransmission, and antitumor action. Among the exogenous NO …
antiparasitic activities, neurotransmission, and antitumor action. Among the exogenous NO …
Ru (II)/NN/PPh3 complexes as potential anticancer agents against MDA-MB-231 cancer cells (NN= diimine or diamine)
GH Ribeiro, L Colina-Vegas, JCT Clavijo… - Journal of Inorganic …, 2019 - Elsevier
The rational design of anticancer agents that acts in specific biological targets is one of the
most effective strategies for developing chemotherapeutic agents. Aiming at obtaining new …
most effective strategies for developing chemotherapeutic agents. Aiming at obtaining new …
Hesperetin as an inhibitor of the snake venom serine protease from Bothrops jararaca
R Vander dos Santos, G Grillo, H Fonseca, D Stanisic… - Toxicon, 2021 - Elsevier
Abstract The majority (90%) of the snakebite envenomation in Brazil accounts for Bothrops
from the Viperidae family. Some snake venom serine proteases provoke blood coagulation …
from the Viperidae family. Some snake venom serine proteases provoke blood coagulation …
Antileishmanial and Anti‐Chikungunya Activity of Cu (I)‐N‐Heterocyclic Carbenes
Neglected tropical diseases such as Leishmaniasis and Chikungunya fever are worldwide
public health challenges mainly affecting tropical and subtropical countries. One cationic [Cu …
public health challenges mainly affecting tropical and subtropical countries. One cationic [Cu …
Ru/Fe bimetallic complexes: Synthesis, characterization, cytotoxicity and study of their interactions with DNA/HSA and human topoisomerase IB
JE Takarada, APM Guedes, RS Correa… - Archives of biochemistry …, 2017 - Elsevier
Three ruthenium/iron-based compounds, 1:[Ru (MIm)(bipy)(dppf)] PF 6 (MIm= 2-mercapto-1-
methylimidazole anion), 2:[RuCl (Im)(bipy)(dppf)] PF 6 (Im= imidazole), and 3:[Ru …
methylimidazole anion), 2:[RuCl (Im)(bipy)(dppf)] PF 6 (Im= imidazole), and 3:[Ru …
Study of nitrogen heterocycles as DNA/HSA binder, topoisomerase inhibitors and toxicological safety
JC Dos Santos, JEF Alves, RDS de Azevedo… - International Journal of …, 2024 - Elsevier
Four new nitrogen-containing heterocyclic derivatives (acridine, quinoline, indole, pyridine)
were synthesized and their biological properties were evaluated. The compounds showed …
were synthesized and their biological properties were evaluated. The compounds showed …
Interaction of the nitrosyl ruthenium complex [RuII (NH.NHq‐R)(tpy)NO]3+ with human serum albumin: a spectroscopic and computational investigation
NC Bessas, LA da Silva, M Comar Júnior… - …, 2021 - Wiley Online Library
The interaction between two nitrosyl ruthenium complexes [Ru (NH. NHq–COOH)(tpy)
NO](PF6) 3 (RuBDQ) and [Ru (NH. NHq–H)(tpy) NO](PF6) 3 (RuBD) and human serum …
NO](PF6) 3 (RuBDQ) and [Ru (NH. NHq–H)(tpy) NO](PF6) 3 (RuBD) and human serum …