40 years after the registration of acyclovir: do we need new anti-herpetic drugs?

A Majewska, B Mlynarczyk-Bonikowska - International journal of …, 2022 - mdpi.com
Herpes simplex virus types 1 and 2 HSV1 and 2, namely varicella-zoster VZV and
cytomegalovirus CMV, are among the most common pathogens worldwide. They remain in …

Herpes simplex virus and varicella zoster virus infections in cancer patients

R Tayyar, D Ho - Viruses, 2023 - mdpi.com
Herpes simplex virus (HSV) and varicella zoster virus (VZV) are alpha herpesviruses that
establish life-long latent infection in neuronal ganglia after primary infection. Periodic …

Diagnosis of herpes simplex virus: laboratory and point-of-care techniques

P Nath, MA Kabir, SK Doust, A Ray - Infectious Disease Reports, 2021 - mdpi.com
Herpes is a widespread viral infection caused by the herpes simplex virus (HSV) that has no
permanent cure to date. There are two subtypes, HSV-1 and HSV-2, that are known to cause …

Trivalent nucleoside-modified mRNA vaccine yields durable memory B cell protection against genital herpes in preclinical models

S Awasthi, JJ Knox, A Desmond… - The Journal of …, 2021 - Am Soc Clin Investig
Nucleoside-modified mRNA vaccines have gained global attention because of COVID-19.
We evaluated a similar vaccine approach for preventing a chronic, latent genital infection …

Towards improved use of vaccination in the control of infectious bronchitis and Newcastle disease in poultry: understanding the immunological mechanisms

AC Ike, CM Ononugbo, OJ Obi, CJ Onu, CV Olovo… - Vaccines, 2021 - mdpi.com
Infectious bronchitis (IB) and Newcastle disease (ND) are two important diseases of poultry
and have remained a threat to the development of the poultry industry in many parts of the …

Identification and Characterization of Long Non-coding RNAs in the Intestine of Olive Flounder (Paralichthys olivaceus) During Edwardsiella tarda Infection

Y Xiu, Y Li, X Liu, L Su, S Zhou, C Li - Frontiers in Immunology, 2021 - frontiersin.org
Long non-coding RNAs (lncRNAs) play widespread roles in fundamental biological
processes, including immune responses. The olive flounder (Paralichthys olivaceus), an …

Roles of emerging RNA-binding activity of cGAS in innate antiviral response

Y Ma, X Wang, W Luo, J Xiao, X Song, Y Wang… - Frontiers in …, 2021 - frontiersin.org
cGAS, a DNA sensor in mammalian cells, catalyzes the generation of 2'-3'-cyclic AMP-GMP
(cGAMP) once activated by the binding of free DNA. cGAMP can bind to STING, activating …

Advancing our understanding of corneal herpes simplex virus-1 immune evasion mechanisms and future therapeutics

E Greenan, S Gallagher, R Khalil, CC Murphy… - Viruses, 2021 - mdpi.com
Herpes stromal keratitis (HSK) is a disease that commonly affects the cornea and external
eye and is caused by Herpes Simplex Virus type 1 (HSV-1). This virus infects approximately …

Immunopathology of herpes simplex virus‐associated neuroinflammation: Unveiling the mysteries

MS Hussain, G Gupta, VP Samuel… - Reviews in Medical …, 2024 - Wiley Online Library
The immunopathology of herpes simplex virus (HSV)‐associated neuroinflammation is a
captivating and intricate field of study within the scientific community. HSV, renowned for its …

Эффективность коррекции цитокинового компонента локального иммунитета в лечении рецидивирующего бактериального вагиноза, ассоциированного с …

БМ Айсаева, ГБ Дикке, ЗА Абусуева… - Вопросы гинекологии …, 2021 - elibrary.ru
Риск бактериального вагиноза (БВ) и частота рецидивов увеличиваются в присутствии
герпесвирусов, что связывают с изменением локальной иммунной защиты. Цель …