[HTML][HTML] The mechanics of mitotic cell rounding

AV Taubenberger, B Baum… - Frontiers in cell and …, 2020 - frontiersin.org
When animal cells enter mitosis, they round up to become spherical. This shape change is
accompanied by changes in mechanical properties. Multiple studies using different …

Microfluidic technologies for cell deformability cytometry

H Chen, J Guo, F Bian, Y Zhao - Smart Medicine, 2022 - Wiley Online Library
Microfluidic detection methods for cell deformability cytometry have been regarded as
powerful tools for single‐cell analysis of cellular mechanical phenotypes, thus having been …

[HTML][HTML] Physical phenotype of blood cells is altered in COVID-19

M Kubánková, B Hohberger, J Hoffmanns, J Fürst… - Biophysical journal, 2021 - cell.com
Clinical syndrome coronavirus disease 2019 (COVID-19) induced by severe acute
respiratory syndrome coronavirus 2 is characterized by rapid spreading and high mortality …

A comparison of microfluidic methods for high-throughput cell deformability measurements

M Urbanska, HE Muñoz, J Shaw Bagnall, O Otto… - Nature …, 2020 - nature.com
The mechanical phenotype of a cell is an inherent biophysical marker of its state and
function, with many applications in basic and applied biological research. Microfluidics …

Cancer cells' ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential

L Wullkopf, AKV West, N Leijnse, TR Cox… - Molecular biology of …, 2018 - Am Soc Cell Biol
Increased tissue stiffness is a classic characteristic of solid tumors. One of the major
contributing factors is increased density of collagen fibers in the extracellular matrix (ECM) …

Intelligent image-based deformation-assisted cell sorting with molecular specificity

AA Nawaz, M Urbanska, M Herbig, M Nötzel, M Kräter… - Nature …, 2020 - nature.com
Although label-free cell sorting is desirable for providing pristine cells for further analysis or
use, current approaches lack molecular specificity and speed. Here, we combine real-time …

Nonlinear microfluidics

D Stoecklein, D Di Carlo - Analytical chemistry, 2018 - ACS Publications
Microfluidic flow is commonly employed in the biological, chemical, or physical analysis of
samples in small fluid volumes because of the typical lack of nonlinear phenomena, with …

Real-time fluorescence and deformability cytometry

P Rosendahl, K Plak, A Jacobi, M Kraeter, N Toepfner… - Nature …, 2018 - nature.com
The throughput of cell mechanical characterization has recently approached that of
conventional flow cytometers. However, this very sensitive, label-free approach still lacks the …

Engineering the deformability of albumin‐stabilized emulsions for lymph‐node vaccine delivery

T Song, Y Xia, Y Du, MW Chen, H Qing… - Advanced …, 2021 - Wiley Online Library
A major challenge in vaccine delivery is to achieve robust lymph‐node (LN) accumulation,
which can capitalize on concentrated immunocytes and cytokines in LNs to stimulate the …

[HTML][HTML] Detection of human disease conditions by single-cell morpho-rheological phenotyping of blood

N Toepfner, C Herold, O Otto, P Rosendahl, A Jacobi… - elife, 2018 - elifesciences.org
Blood is arguably the most important bodily fluid and its analysis provides crucial health
status information. A first routine measure to narrow down diagnosis in clinical practice is the …