[HTML][HTML] The nucleosome: from genomic organization to genomic regulation
S Khorasanizadeh - Cell, 2004 - cell.com
Electron micrographs first confirmed that the eukaryotic genome is organized into repeating
disk-shaped nucleosomal units composed of histones and their associated DNA. Those …
disk-shaped nucleosomal units composed of histones and their associated DNA. Those …
Histone structure and the organization of the nucleosome
V Ramakrishnan - Annual review of biophysics and biomolecular …, 1997 - annualreviews.org
▪ Abstract Chromatin structure is now believed to be dynamic and intimately related with
cellular processes such as transcription. Over the past few years, high-resolution structures …
cellular processes such as transcription. Over the past few years, high-resolution structures …
Crystal structure of the nucleosome core particle at 2.8 Å resolution
K Luger, AW Mäder, RK Richmond, DF Sargent… - Nature, 1997 - nature.com
The X-ray crystal structure of the nucleosome core particle of chromatin shows in atomic
detail how the histone protein octamer is assembled and how 146 base pairs of DNA are …
detail how the histone protein octamer is assembled and how 146 base pairs of DNA are …
Crystal structures of nucleosome core particles containing the '601'strong positioning sequence
Nucleosome positioning plays a key role in genomic regulation by defining histone–DNA
context and by modulating access to specific sites. Moreover, the histone–DNA register …
context and by modulating access to specific sites. Moreover, the histone–DNA register …
Characterization of nucleosome core particles containing histone proteins made in bacteria
The four core histone proteins, H2A, H2B, H3, and H4 of Xenopus laevis have been
individually expressed in milligram quantities in Escherichia coli. The full-length proteins …
individually expressed in milligram quantities in Escherichia coli. The full-length proteins …
CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere
Inheritance of each chromosome depends upon its centromere. A histone H3 variant,
centromere protein A (CENP-A), is essential for epigenetically marking centromere location …
centromere protein A (CENP-A), is essential for epigenetically marking centromere location …
Methylation of histone H3 by coactivator-associated arginine methyltransferase 1
BT Schurter, SS Koh, D Chen, GJ Bunick, JM Harp… - Biochemistry, 2001 - ACS Publications
The preferential in vitro methylation of histone H3 by coactivator-associated arginine
methyltransferase 1 (CARM1) has been proposed as a basis for its ability to enhance gene …
methyltransferase 1 (CARM1) has been proposed as a basis for its ability to enhance gene …
Asymmetries in the nucleosome core particle at 2.5 Å resolution
The 2.5 Å X-ray crystal structure of the nucleosome core particle presented here provides
significant additions to the understanding of the nucleosome, the fundamental unit of …
significant additions to the understanding of the nucleosome, the fundamental unit of …
Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment
Genomic DNA in eukaryotes is organized into chromatin through association with core
histones to form nucleosomes, each distinguished by their DNA sequences and histone …
histones to form nucleosomes, each distinguished by their DNA sequences and histone …
CENP-C directs a structural transition of CENP-A nucleosomes mainly through sliding of DNA gyres
The histone H3 variant CENP-A is incorporated into nucleosomes that mark centromere
location. We have recently reported that CENP-A nucleosomes, compared with their H3 …
location. We have recently reported that CENP-A nucleosomes, compared with their H3 …