Dysfunctional dopamine (DA) signaling has been associated with a broad spectrum of
neuropsychiatric disorders, prompting investigations into how midbrain DA neuron …

Social homeostasis is the ability of individuals to detect the quantity and quality of social
contact, compare it to an established set-point in a command center, and adjust the effort …

The motivation to seek social contact may arise from either positive or negative emotional
states, as social interaction can be rewarding and social isolation can be aversive. While …

The dorsal raphe nucleus (DRN) is an important source of neuromodulators and has been
implicated in a wide variety of behavioral and neurological disorders. The DRN is …

Ventral midbrain dopamine (DA) is unambiguously involved in motivation and behavioral
arousal, yet the contributions of other DA populations to these processes are poorly …

In nature, both males and females engage in competitive aggressive interactions to resolve
social conflicts, yet the behavioral principles guiding such interactions and their underlying …

Social connections are vital to survival throughout the animal kingdom and are dynamic
across the life span. There are debilitating consequences of social isolation and loneliness …

Effective approaches to neuropsychiatric disorders require detailed understanding of the
cellular composition and circuitry of the complex mammalian brain. Here, we present a …

The dorsal raphe nucleus (DRN) contains the largest group of serotonin-producing neurons
in the brain and projects to regions controlling reward. Although pharmacological studies …

The periaqueductal gray (PAG) is a brain region involved in nociception modulation, and an
important relay center for the descending nociceptive pathway through the rostral ventral …