Liver transplantation is the most effective treatment of advanced liver disease, and the use of
extended criteria donor organs has broadened the source of available livers. Although …

Background: Liver transplantation is a lifesaving procedure for patients with end-stage liver
disease (ESLD). However, many patients never receive a transplant due to insufficient donor …

To alleviate the persistent shortage of donor livers, high‐risk liver grafts are increasingly
being considered for liver transplantation. Conventional preservation with static cold storage …

Although normothermic machine perfusion (NMP) provides superior preservation of liver
grafts compared to static cold storage and allows for viability testing of high-risk grafts, its …

Predicting organ viability before transplantation remains one of the most challenging and
ambitious objectives in transplant surgery. Waitlist mortality is high while transplantable …

Background. The successful implementation of end-ischemic normothermic machine
perfusion (NMP) into clinical practice comes along with unusual demands for trained …

Robust viability assessment of grafts during normothermic liver perfusion is a prerequisite for
organ use. Coagulation parameters are used commonly for liver assessment in patients …

The need for donor pool expansion in liver transplantation has increased utilization of grafts
from so-called extended-criteria donors. Machine perfusion technology can improve …

Background Normothermic machine perfusion (NMP) is used for preservation and
assessment of human donor livers prior to transplantation. During NMP, the liver is …

Porcine models of liver ex situ normothermic machine perfusion (NMP) are increasingly
being used in transplant research. Contrary to rodents, porcine livers are anatomically and …