The appearance of cognitive deficits and altered brain morphology in newborns with Down
syndrome (DS) suggests that these features are driven by disruptions at the earliest stages …

The nervous system is the most complex system in the human body, and the normal
development of the central nervous system (CNS) is essential for maintaining the healthy life …

Abstract Autism Spectrum Disorder (ASD) is caused by genetic, epigenetic, and
environmental factors. Mutations in the human FMR1 gene, encoding the Fragile X …

The human genome has many short tandem repeats, yet the normal functions of these
repeats are unclear. The 5′ untranslated region (UTR) of the fragile X messenger …

FMRP gains mitochondrial fission control | Nature Cell Biology Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Synapses of the neocortex specialized during human evolution to develop over extended
timescales, process vast amounts of information and increase connectivity, which is thought …

Human brain organoid models have emerged as a promising tool for studying human brain
development and function. These models preserve human genetics and recapitulate some …

The finely tuned regulation of mitochondria activity is essential for proper brain development.
Fragile X Syndrome (FXS), the leading cause of inherited intellectual disability, is a …

There are substantial differences in the characteristics of males and females with an autism
spectrum disorder (ASD), yet there is little knowledge surrounding the mechanistic …

Abstract Fragile X Syndrome (FXS) is a neurodevelopment disorder characterized by
cognitive impairment, behavioral challenges, and synaptic abnormalities, with a genetic …