Neuronal circuitry for recognition memory of object and place in rodent models
Rats and mice are used for studying neuronal circuits underlying recognition memory due to
their ability to spontaneously remember the occurrence of an object, its place and an …
their ability to spontaneously remember the occurrence of an object, its place and an …
[HTML][HTML] An integrated index: engrams, place cells, and hippocampal memory
The hippocampus and its extended network contribute to encoding and recall of episodic
experiences. Drawing from recent anatomical, physiological, and behavioral studies, we …
experiences. Drawing from recent anatomical, physiological, and behavioral studies, we …
Hippocampal CA2 sharp-wave ripples reactivate and promote social memory
The consolidation of spatial memory depends on the reactivation ('replay') of hippocampal
place cells that were active during recent behaviour. Such reactivation is observed during …
place cells that were active during recent behaviour. Such reactivation is observed during …
A hypothalamic novelty signal modulates hippocampal memory
The ability to recognize information that is incongruous with previous experience is critical
for survival. Novelty signals have therefore evolved in the mammalian brain to enhance …
for survival. Novelty signals have therefore evolved in the mammalian brain to enhance …
A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics
Recent results suggest that social memory requires the dorsal hippocampal CA2 region as
well as a subset of ventral CA1 neurons. However, it is unclear whether dorsal CA2 and …
well as a subset of ventral CA1 neurons. However, it is unclear whether dorsal CA2 and …
The hippocampal engram maps experience but not place
Episodic memories are encoded by a sparse population of hippocampal neurons. In mice,
optogenetic manipulation of this memory engram established that these neurons are …
optogenetic manipulation of this memory engram established that these neurons are …
Coding of social novelty in the hippocampal CA2 region and its disruption and rescue in a 22q11. 2 microdeletion mouse model
The hippocampal CA2 region is essential for social memory. To determine whether CA2
activity encodes social interactions, we recorded extracellularly from CA2 pyramidal neurons …
activity encodes social interactions, we recorded extracellularly from CA2 pyramidal neurons …
Social memory and the role of the hippocampal CA2 region
N Tzakis, MR Holahan - Frontiers in behavioral neuroscience, 2019 - frontiersin.org
The CA2 region of the hippocampus is a somewhat obscure area lacking in an
understanding of its form and function. Until recently, the CA2 has been thought of as merely …
understanding of its form and function. Until recently, the CA2 has been thought of as merely …
Persistence of neuronal representations through time and damage in the hippocampus
How do neurons encode long-term memories? Bilateral imaging of neuronal activity in the
mouse hippocampus reveals that, from one day to the next,~ 40% of neurons change their …
mouse hippocampus reveals that, from one day to the next,~ 40% of neurons change their …
Chondroitin 4-O-sulfation regulates hippocampal perineuronal nets and social memory
H Huang, AM Joffrin, Y Zhao… - Proceedings of the …, 2023 - National Acad Sciences
Glycan alterations are associated with aging, neuropsychiatric, and neurodegenerative
diseases, although the contributions of specific glycan structures to emotion and cognitive …
diseases, although the contributions of specific glycan structures to emotion and cognitive …