Sleep is a cyclically occurring, transient, and functional state that is controlled primarily by
neurobiological processes. Sleep disorders and insomnia are increasingly being diagnosed …

Sleep abnormalities are associated with acute and chronic use of addictive substances.
Although sleep complaints associated with use and abstinence from addictive substances …

Background The use of cannabis, or marijuana, for medicinal purposes is deeply rooted
though history, dating back to ancient times. It once held a prominent position in the history …

Sleep is a vital function of the nervous system that contributes to brain and bodily
homeostasis, energy levels, cognitive ability, and other key functions of a variety of …

We conducted a double-blind, placebo-controlled, crossover study evaluating the analgesic
efficacy of vaporized cannabis in subjects, the majority of whom were experiencing …

A comparative risk assessment of drugs including alcohol and tobacco using the margin of
exposure (MOE) approach was conducted. The MOE is defined as ratio between …

Perspectives on the P300 event-related brain potential (ERP) are reviewed by outlining the
distinction between the P3a and P3b subcomponents. The critical factor for eliciting P3a is …

The authors review the literature examining the validity and significance of cannabis
withdrawal syndrome. Findings from animal laboratory research are briefly reviewed, and …

Previous studies have reported conflicting results in terms of acute effects of cannabis in
man. Independently of other factors, such discrepancy may be attributable to the different …

Withdrawal symptoms following cessation of heavy cannabis (marijuana) use have been
reported, yet their time course and clinical importance have not been established. A 50-day …