Heme oxygenases are composed of two isozymes, Hmox1 and Hmox2, that catalyze the
degradation of heme to carbon monoxide (CO), ferrous iron, and biliverdin, the latter of …

Carbon monoxide (CO) is emerging as an important and versatile mediator of physiological
processes to the extent that treatment of animals with exogenous CO gas has beneficial …

Iron-derived reactive oxygen species are involved in the pathogenesis of numerous vascular
disorders. One abundant source of redox active iron is heme, which is inherently dangerous …

Iron‐derived reactive oxygen species are implicated in the pathogenesis of numerous
vascular disorders including atherosclerosis, microangiopathic hemolytic anemia, vasculitis …

The inverse association between alcohol intake and coronary heart disease has been
consistently reported in cross-culture, case–control, and cohort studies. Over the past couple …

Recent studies have demonstrated that resveratrol (trans-3, 4′, 5-trihydroxy stilbene), a
phytoalexin found in the skin and seeds of grapes, can pharmacologically precondition (PC) …

The effects of kernel extract obtained from sour cherry (Prunus cerasus) seed on the
postischemic cardiac recovery were studied in isolated working rat hearts. Rats were treated …

Objectives To determine whether or not the antioxidants N-acetylcysteine (NAC) and
allopurinol (ALP) confer synergistic cardioprotection against myocardial …

Objective The effects of resveratrol treatment on ventricular arrhythmia, survival, and late
cardiac remodeling were evaluated in rats with myocardial infarction (MI). Methods Three …

Sildenafil citrate (SC), a drug for erectile dysfunction, is now emerging as a cardiopulmonary
drug. Our study aimed to determine a novel role of sildenafil on cardioprotection through …